Totals
- Total revenue
- $53,611,444
- Total expenses
- $64,203,698
- Contributions and grants received
- $52,978,731
- Grants paid
- $8,572,720
- Program service revenue
- $0
- Investment income
- $632,713
- Other revenue
- $0
- Total assets, end of year
- $155,698,196
- Total liabilities, end of year
- $93,814,180
- Net assets or fund balances, end of year
- $61,884,016
- Program services expenses (Part IX)
- $49,064,708
- Management and general expenses
- $15,138,990
- Fundraising expenses
- $0
- Program service expenses (Part III)
- $49,064,708
Program services were 76.4% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.
Line items
Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.
Revenue
Part VIII, the statement of revenue.
-
1f · All other contributions, gifts and grants
$52,978,731
-
2f · All other program service revenue
total $0 · related or exempt $0 · unrelated business $0 · excluded $0
-
3 · Investment income
total $632,713 · excluded $632,713
-
6c · Rental income or loss
real property $0 · personal property $0
-
7c · Gain or loss
securities $0 · other assets $0
-
11d · All other revenue
total $0 · related or exempt $0 · unrelated business $0 · excluded $0
-
11e · Other revenue, total
$0
Functional expenses
Part IX, the statement of functional expenses.
-
1 · Grants to domestic organizations and governments
total $8,572,720 · program services $8,572,720
-
5 · Compensation of officers, directors and key employees
total $3,193,251 · program services $1,801,861 · management and general $1,391,390
-
7 · Other salaries and wages
total $10,792,988 · program services $6,090,178 · management and general $4,702,810
-
8 · Pension plan contributions
total $296,275 · program services $167,179 · management and general $129,096
-
9 · Other employee benefits
total $1,095,670 · program services $661,101 · management and general $434,569
-
10 · Payroll taxes
total $881,758 · program services $510,090 · management and general $371,668
-
11a · Fees: management
total $829,742 · program services $746,768 · management and general $82,974
-
11b · Fees: legal
total $1,055,228 · management and general $1,055,228
-
11c · Fees: accounting
total $67,118 · management and general $67,118
-
11g · Fees: other
total $3,053,825 · program services $210,464 · management and general $2,843,361 · fundraising $0
-
12 · Advertising and promotion
total $83,469 · program services $8,732 · management and general $74,737
-
13 · Office expenses
total $609,434 · program services $133,197 · management and general $476,237
-
16 · Occupancy
total $14,899,739 · program services $13,409,882 · management and general $1,489,857
-
17 · Travel
total $649,574 · program services $359,093 · management and general $290,481
-
19 · Conferences, conventions and meetings
total $127,727 · program services $21,918 · management and general $105,809
-
22 · Depreciation, depletion and amortization
total $7,814,257 · program services $7,032,831 · management and general $781,426
-
23 · Insurance
total $145,099 · management and general $145,099
-
24a · Other expenses: Lab expenses
total $6,904,314 · program services $6,903,182 · management and general $1,132
-
24b · Other expenses: Student expenses
total $1,209,582 · program services $1,209,582
-
24c · Other expenses: Subscriptions
total $1,011,248 · program services $629,566 · management and general $381,682
-
24d · Other expenses: Health and safety expenses
total $317,509 · program services $317,509
-
24e · All other expenses
total $593,171 · program services $278,855 · management and general $314,316 · fundraising $0
Balance sheet
Part X, book values.
-
1 · Cash, non-interest-bearing
beginning of year $38,341,866 · end of year $4,091,658
-
2 · Savings and temporary cash investments
beginning of year $618,831 · end of year $618,831
-
4 · Accounts receivable
beginning of year $11,357 · end of year $6,564
-
5 · Loans and receivables from officers and key people
beginning of year $0 · end of year $0
-
6 · Loans and receivables from disqualified persons
beginning of year $0 · end of year $0
-
9 · Prepaid expenses and deferred charges
beginning of year $1,429,524 · end of year $1,232,853
-
10a · Land, buildings and equipment: cost or other basis
$99,499,504
-
10b · Land, buildings and equipment: accumulated depreciation
$8,616,377
-
10c · Land, buildings and equipment, net
beginning of year $47,856,273 · end of year $90,883,127
-
12 · Investments: other securities
beginning of year $1,000,000 · end of year $1,000,000
-
13 · Investments: program-related
beginning of year $0
-
14 · Intangible assets
beginning of year $0
-
15 · Other assets
beginning of year $60,857,768 · end of year $57,865,163
-
17 · Accounts payable and accrued expenses
beginning of year $8,439,343 · end of year $11,494,900
-
22 · Loans and payables to officers and key people
beginning of year $0 · end of year $0
-
24 · Unsecured notes and loans payable
beginning of year $0 · end of year $16,080,816
-
25 · Other liabilities
beginning of year $69,200,006 · end of year $66,238,464
-
27 · Net assets without donor restrictions
beginning of year $72,476,270 · end of year $61,884,016
Mission and programs · 2023
Mission
Our mission is to accelerate scientific progress, understand the root causes of disease, and narrow the gap between discoveries and impact on patients.
Activities or mission (Part I)
Our mission is to accelerate scientific progress and understand the root causes of complex diseases. This challenge requires researchers across many disciplines to study fundamental biological mechanisms, develop new technologies, and innovate on therapeutic concepts. By doing this, we aim to improve human health by narrowing the gap between discoveries and impact on patients.
-
Headquartered in Palo Alto, California, Arc is a nonprofit research organization founded on the belief that many important scientific programs can be enabled by new organizational models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley. Arc gives scientists no-strings-attached, multi-year funding, so that they don't have to apply for external grants, and INSTEAD CAN invest in the rapid development of experimental and computational technological tools. As individuals, Arc researchers collaborate across diverse disciplines to study complex diseases, including cancer, neurodegeneration, and immune dysfunction. As an organization, Arc strives to enable ambitious, long-term research agendas. The Gilbert lab's expertise is in synthetic biology, functional genomics and cancer biology. We build CRISPR epigenetic editing tools to turn genes on and off and to perturb gene regulatory elements. We are developing CRISPR functional genomics approaches to map individual genes or sets of genes that regulate phenotypes of interest in vitro and in vivo. We are focused on utilizing our expertise to tackle big problems in deadly human cancers such as metastasis and drug resistance. The Hsu Lab works at the intersection of synthetic biology and genomics to invent new biotechnologies for improving human health. The Konermann lab develops and applies next-generation functional genomics to understand the cellular and molecular pathways underlying the neuronal system and neurodegenerative disease, with the long-term goal of developing rationally targeted therapeutics for neurodegenerative disorders. At the Li Lab we combine chemistry, biochemistry, immunology, and physiology to uncover basic mechanisms in innate immunity and, in parallel, develop therapeutic hypotheses and lead molecules. Innate immune pathways as the first line of defense against pathogens present many exciting opportunities for scientists from many disciplines. These pathways are a rich source of novel chemistry: they involve diverse molecular patterns in pathogens, little-explored second messengers, and drugs with poorly understood mechanism. Activation of innate immunity is a proven therapeutic strategy for vaccination, viral infection, and cancer, while inhibition is a strategy for treating autoimmune diseases and neurodegeneration. To date, however, most modulators of innate immunity are broad, non-specific, and poorly characterized, such as killed bacteria, alum crystals, and steroids. The Li lab seeks to improve understanding of these pathways and facilitate the development of more precise drugs for preventing or treating specific diseases.
Expenses $49,064,708 · Grants $8,572,720
As filed on the 2023 return.
Listed in Part VII
-
Nathaniel Friedman
Secretary/Director
- Total calculated
- $36,000
- From this org
- $36,000
- From related orgs
- $0
- Other
- $0
- Hours/week
- 1
-
Alden J Woodrow
COO
- Total calculated
- $777,341
- From this org
- $742,239
- From related orgs
- $0
- Other
- $35,102
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $381,399
- Bonus
- $360,600
- Other
- $240
- Deferred
- $16,500
- Nontaxable benefits
- $18,602
- Filer's total
- $777,341
-
Daniel Dever PhD
Head of Scientific Operations
- Total calculated
- $125,907
- From this org
- $117,098
- From related orgs
- $0
- Other
- $8,809
- Hours/week
- 40
-
Julia M Kazaks
General Counsel
- Total calculated
- $390,872
- From this org
- $365,174
- From related orgs
- $0
- Other
- $25,698
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $317,722
- Bonus
- $46,900
- Other
- $552
- Deferred
- $16,500
- Nontaxable benefits
- $9,198
- Filer's total
- $390,872
-
Lynn M Hendrickson
University Relations & Academic Affairs
- Total calculated
- $352,565
- From this org
- $338,360
- From related orgs
- $0
- Other
- $14,205
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $279,320
- Bonus
- $58,800
- Other
- $240
- Deferred
- $14,205
- Nontaxable benefits
- $0
- Filer's total
- $352,565
-
Nicolle D Seuss
Senior Operations Program Manager
- Total calculated
- $291,589
- From this org
- $270,911
- From related orgs
- $0
- Other
- $20,678
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $229,898
- Bonus
- $40,500
- Other
- $513
- Deferred
- $13,840
- Nontaxable benefits
- $6,838
- Filer's total
- $291,589
-
Patrick D Hsu PhD
Core Investigator
- Total calculated
- $524,132
- From this org
- $504,392
- From related orgs
- $0
- Other
- $19,740
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $457,280
- Bonus
- $46,920
- Other
- $192
- Deferred
- $16,500
- Nontaxable benefits
- $3,240
- Filer's total
- $524,132
-
Rose E Harris
Finance
- Total calculated
- $151,655
- From this org
- $151,655
- From related orgs
- $0
- Other
- $0
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $130,320
- Bonus
- $21,200
- Other
- $135
- Deferred
- $0
- Nontaxable benefits
- $0
- Filer's total
- $151,655
-
Silvana M Konermann PhD
Executive Director
- Total calculated
- $226,686
- From this org
- $225,268
- From related orgs
- $0
- Other
- $1,418
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $204,502
- Bonus
- $20,600
- Other
- $166
- Deferred
- $0
- Nontaxable benefits
- $1,418
- Filer's total
- $226,686
-
Susan Cull
Senior Finance
- Total calculated
- $163,576
- From this org
- $156,004
- From related orgs
- $0
- Other
- $7,572
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $149,754
- Bonus
- $6,000
- Other
- $250
- Deferred
- $7,572
- Nontaxable benefits
- $0
- Filer's total
- $163,576
-
Therese Costello
Head of People
- Total calculated
- $152,930
- From this org
- $146,619
- From related orgs
- $0
- Other
- $6,311
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $146,095
- Bonus
- $400
- Other
- $124
- Deferred
- $5,833
- Nontaxable benefits
- $478
- Filer's total
- $152,930
-
Benjamin N Mijts
Senior Director, Genome Engineering Technology Center
- Total calculated
- $280,219
- From this org
- $259,934
- From related orgs
- $0
- Other
- $20,285
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $252,098
- Bonus
- $7,500
- Other
- $336
- Deferred
- $12,625
- Nontaxable benefits
- $7,660
- Filer's total
- $280,219
-
Jennifer A Moss
Senior Recruiter
- Total calculated
- $357,568
- From this org
- $341,470
- From related orgs
- $0
- Other
- $16,098
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $271,026
- Bonus
- $70,100
- Other
- $344
- Deferred
- $16,098
- Nontaxable benefits
- $0
- Filer's total
- $357,568
-
Lingyin Li
Core Investigator
- Total calculated
- $290,224
- From this org
- $283,866
- From related orgs
- $0
- Other
- $6,358
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $236,041
- Bonus
- $47,600
- Other
- $225
- Deferred
- $2,479
- Nontaxable benefits
- $3,879
- Filer's total
- $290,224
-
Luke Gilbert
CORE INVESTIGATOR
- Total calculated
- $294,436
- From this org
- $279,098
- From related orgs
- $0
- Other
- $15,338
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $232,502
- Bonus
- $46,400
- Other
- $196
- Deferred
- $13,920
- Nontaxable benefits
- $1,418
- Filer's total
- $294,436
-
Nianzhen Li PHD
Senior Director, Multi-omics technology development
- Total calculated
- $278,190
- From this org
- $274,094
- From related orgs
- $0
- Other
- $4,096
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $259,150
- Bonus
- $14,600
- Other
- $344
- Deferred
- $3,918
- Nontaxable benefits
- $178
- Filer's total
- $278,190
Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us.
Schedule J
Answered yes
- 1a · Tax indemnification and gross-up payments
- 3 · Independent compensation consultant
- 3 · Compensation survey or study
- 3 · Approval by the board or compensation committee
- 4a · Severance or change-of-control payment
- 7 · Other non-fixed payments
Answered no
- 4b · Supplemental nonqualified retirement plan
- 4c · Equity-based compensation arrangement
- 5a · Pay contingent on this organization's revenues
- 5b · Pay contingent on a related organization's revenues
- 6a · Pay contingent on this organization's net earnings
- 6b · Pay contingent on a related organization's net earnings
- 8 · Paid under the initial-contract exception
The filer's explanations (Part III)
- Schedule J, Part I, Line 1a Tax indemnification and gross-up payments
- 2 executives received tax gross-up payments. These are treated as taxable compensation to individuals.
- Schedule J, Part I, Line 4a Severance or change-of-control payment
- THE FOLLOWING INDIVIDUALS RECEIVED SEVERANCE PAY DURING 2023 (INCLUDED IN SCHEDULE J, PART II, COLUMN (B)(III): BENJAMIN N MIJTS - $ JENNIFER A MOSS - $ DANIEL DEVER, PHD - $
- Schedule J, Part I, Line 7 Non-fixed payments
- For each full year of employment with the Institute, individuals shall be eligible to earn an annual bonus of up to a percentage of their effective Base Salary ("Annual Bonus"), based half on their and half on the Institute's achievement of performance goals established in advance by the Board of Directors of the Institute ("Board") or its delegate and provided in writing, contingent on the individuals remaining actively employed with the Institute through the payment date of each Annual Bonus. The Annual Bonus will be prorated based on start date. The Annual Bonus, if any, will be earned and paid no later than two and a half months after the end of the fiscal year, at which point the Board (or its delegate) will also have determined goals for the then current fiscal year. All bonus payments shall be made less deductions and withholdings required by law or approved by the individuals. COO Bonus program: For each year of employment with the Institute, the COO shall be eligible to earn a discretionary bonus, on a semi-annual basis, in the target amount of 50% of their then effective Base Salary, based on: (a) the extent of their achievement against individual performance goals set for each semi-annual period, and (b) overall performance rating for that semi-annual period ("Individual Performance Bonus"). The goals for each bonus period will be mutually agreed upon between the COO and the Institute and provided in writing. In each semi-annual period, if the COO achieves the goals and receives a performance rating of "3 - Exemplary," they will be eligible for the target bonus amount (50% of Base Salary). If they achieve fewer than all goals or receive a performance rating of "2 - Success," they will be eligible for a partial bonus in an amount deemed appropriate for the level of performance. If they receive a performance rating of "1 - Missed Expectations," they will not be eligible for any bonus for the period. Decisions concerning performance ratings, whether they receive an Individual Performance Bonus in any semi-annual period, and the amount of any such bonus, shall be at the Institute's discretion. Each Individual Performance Bonus, if awarded, will be paid by April 30 or October 31, as applicable. Eligibility to receive any Individual Performance Bonus payment is contingent upon the COO remaining actively employed with the Institute through the scheduled payment date. All bonus payments will be made less deductions and withholdings required by law or approved by the COO.
Part I's answers as filed. A line not listed was left unanswered; on lines 1a and 3 that means the box was not checked.
Grants on this return
-
University of California San Francisco
$4,000,000
Goldberg-Benioff Endowed Professorship in Prostate Cancer Translational Biology
-
$3,482,720
University Fellowships
-
$540,000
Ignite Award Recipients Katrin Andreasson, Michael Fischbach, Calvin Kuo, Xiaojie Qiu, Julia Salzman
-
Ignite Awards to Fattahi, Kampmann, Pollen, Yang
-
UNIVERSITY OF CALIFORNIA BERKELEY
$110,000
Ignite Award to Robert Saxton
Taxable family on this return
Schedule R Parts I, III and IV, as filed. These record ownership and control, not shared board members or money moved.
Disregarded entities
Part I: entities that legally are the filer and file no return of their own.
-
ARC MOBILITY LLC
TRANSPORTATION · DE · income $0 · assets $0
Directly controlled by ARC RESEARCH INSTITUTE
Provenance
- Return type
- form_990
- Tax year
- 2023
- Filed
- 13 November 2024
- IRS schema version
- 2023v5.1
- Source object
- 202423189349308952
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