Totals
- Total revenue
- $48,489,989
- Total expenses
- $80,949,362
- Contributions and grants received
- $0
- Grants paid
- $44,025,060
- Program service revenue
- $0
- Investment income
- $48,489,989
- Other revenue
- $0
- Total assets, end of year
- $1,099,305,270
- Total liabilities, end of year
- $37,520,177
- Net assets or fund balances, end of year
- $1,061,785,093
- Program services expenses (Part IX)
- $78,588,857
- Management and general expenses
- $2,360,505
- Fundraising expenses
- $0
- Program service expenses (Part III)
- $78,588,857
Program services were 97.1% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.
Line items
Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.
Revenue
Part VIII, the statement of revenue.
-
3 · Investment income
total $35,179,504 · excluded $35,179,504
-
7a · Gross sales of assets other than inventory
securities $34,338,298
-
7b · Less cost or other basis and sales expenses
securities $21,027,813
-
7c · Gain or loss
securities $13,310,485
-
7d · Net gain or loss
total $13,310,485 · excluded $13,310,485
Functional expenses
Part IX, the statement of functional expenses.
-
1 · Grants to domestic organizations and governments
total $43,025,060 · program services $43,025,060
-
3 · Grants to foreign organizations and individuals
total $1,000,000 · program services $1,000,000
-
11b · Fees: legal
total $1,513,577 · program services $1,242,633 · management and general $270,944
-
11c · Fees: accounting
total $53,050 · management and general $53,050
-
11g · Fees: other
total $4,205,273 · program services $2,239,745 · management and general $1,965,528
-
13 · Office expenses
total $2,035 · program services $667 · management and general $1,368
-
14 · Information technology
total $8,453 · program services $3,200 · management and general $5,253
-
17 · Travel
total $50,637 · program services $50,637
-
19 · Conferences, conventions and meetings
total $1,023,284 · program services $1,023,284
-
23 · Insurance
total $47,395 · management and general $47,395
-
24a · Other expenses: R&D COLLABORATIVE EXP
total $30,000,000 · program services $30,000,000
-
24b · Other expenses: STATE TAXES
total $13,100 · management and general $13,100
-
24c · Other expenses: MEALS & ENTERTAINMENT
total $3,481 · program services $3,481
-
24d · Other expenses: LICENSES & FEES
total $3,290 · program services $150 · management and general $3,140
-
24e · All other expenses
total $727 · management and general $727
Balance sheet
Part X, book values.
-
1 · Cash, non-interest-bearing
beginning of year $6,630,202 · end of year $40,317
-
2 · Savings and temporary cash investments
beginning of year $843,467,574 · end of year $400,957,971
-
4 · Accounts receivable
beginning of year $43,087 · end of year $57,948
-
9 · Prepaid expenses and deferred charges
beginning of year $268,250 · end of year $0
-
12 · Investments: other securities
beginning of year $289,106,549 · end of year $698,249,034
-
17 · Accounts payable and accrued expenses
beginning of year $375,598 · end of year $637,964
-
18 · Grants payable
beginning of year $59,000,000 · end of year $36,882,213
-
27 · Net assets without donor restrictions
beginning of year $1,080,140,064 · end of year $1,061,785,093
Mission and programs · 2024
Mission
TO FOSTER, SUPPORT, PROMOTE AND CONDUCT ACTIVITIES DESIGNED TO BENEFIT AND IMPROVE THE ENVIRONMENT AND GLOBAL HEALTH.
Activities or mission (Part I)
FOSTER, SUPPORT, AND CONDUCT ACTIVITIES TO IMPROVE THE ENVIRONMENT AND GLOBAL HEALTH.
-
SUPPORT FOR INITIATIVES AND EFFORTS THAT ADDRESS CLIMATE AND ENVIRONMENTAL CHALLENGES, FOCUSING ON REDUCING EMISSIONS, ADVANCING CLEAN ENERGY SOLUTIONS, AND PROMOTING ENVIRONMENTAL SUSTAINABILITY AND RESILIENCE TO CLIMATE IMPACTS.
Expenses $41,733,204 · Grants $40,875,060
-
SUPPORT FOR RESEARCH AND DEVELOPMENT RELATED TO CENTRAL NERVOUS SYSTEM ("CNS") NEUROLOGICAL DISEASES/DISORDERS (SUCH AS PARKINSON'S, ALZHEIMER'S, ALS, AUTISM, DEMENTIA, BIPOLAR, EPILEPSY, AND NEUROPATHIC PAIN).
Expenses $36,855,653 · Grants $3,150,000
As filed on the 2024 return.
Listed in Part VII
-
Robert BrownROBERT BROWN
PRESIDENT/DIRECTOR
- Total calculated
- $0
- Hours/week
- 10
-
Mark VorsatzMARK VORSATZ
DIRECTOR
- Total calculated
- $0
- Hours/week
- 0.8
-
Ekemini RileyEKEMINI RILEY
DIRECTOR
- Total calculated
- $0
- Hours/week
- 0.5
-
Tara FarnsworthTARA FARNSWORTH
SECRETARY & TREASURER
- Total calculated
- $0
- Hours/week
- 1
Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those.
Grants on this return
-
$25,000,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
$6,600,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
LEAGUE OF CONSERVATION VOTERS INC
$3,545,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
$3,150,000
FOR THE PURPOSE OF CENTRAL NERVOUS SYSTEM ("CNS") PROGRAMS
-
$2,555,060
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
$1,200,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
$550,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
ENVIRONMENTAL DEFENSE ACTION FUND
$400,000
FOR THE PURPOSE OF ENVIRONMENTAL PROGRAMS
-
WASTEWATER ACTION ALLIANCE INC
$25,000
FOR THE PURPOSE TO IMPROVE GLOBAL HEALTH
Taxable family on this return
Schedule R Parts I, III and IV, as filed. These record ownership and control, not shared board members or money moved.
Disregarded entities
Part I: entities that legally are the filer and file no return of their own.
-
CURARE CNS LLC
INVESTMENT · DE · income $0 · assets $15,317
Directly controlled by CATALYST4 INC
Related partnerships
Part III: related organizations taxable as a partnership, with the filer's share.
-
THE COLUMN GROUP-NEURO LP
EXCLUDED · INVESTMENT · CA · 74.25% owned · share of income $249,964 · share of assets $60,249,547
Directly controlled by CATALYST4 INC
-
NEXUS NEUROTECH FUND I LP
EXCLUDED · INVESTMENT · CA · 94.82% owned · share of income $4,094 · share of assets $34,008,004
Directly controlled by CATALYST4 INC
-
HOMECOMING CAPITAL LLC
EXCLUDED · INVESTMENT · CA · 100% owned · share of income $19,574,819 · share of assets $17,440,164
Directly controlled by CATALYST4 INC
-
NEXUS NEUROTECH SPV I LP
EXCLUDED · INVESTMENT · CA · 94.5% owned · share of assets $7,673,416
Directly controlled by CATALYST4 INC
-
NEXUS NEUROTECH SPV II LP
EXCLUDED · INVESTMENT · CA · 94.5% owned · share of assets $4,814,919
Directly controlled by CATALYST4 INC
-
NEXUS NEUROTECH SPV III LP
EXCLUDED · INVESTMENT · CA · 95% owned · share of assets $14,340,487
Directly controlled by CATALYST4 INC
-
THE COLUMN GROUP-NEURO II LP
EXCLUDED · INVESTMENT · CA · 74.94% owned · share of assets $401,748
Directly controlled by CATALYST4 INC
Related corporations and trusts
Part IV: related organizations taxable as a corporation or trust.
-
MAPLIGHT THERAPEUTICS INC
C · BIOPHARMACEUTICAL · DE · 55.4% owned · share of income $2,972,764 · share of assets $75,851,464 · controlled entity
Directly controlled by CATALYST4 INC
-
BRIDGE ANALYTICS DATA AND SCIENCE SERVICES INC
C · DATA ANALYSIS · DE · 100% owned · share of assets $76,085 · controlled entity
Directly controlled by CATALYST4 INC
-
SONEIRA INC PBC
C · BIOPHARMACEUTICAL · DE · 56.05% owned · share of income $69,301 · share of assets $1,852,501 · controlled entity
Directly controlled by CATALYST4 INC
-
STELLAROMICS INC
C · BIOPHARMACEUTICAL · DE · 75.09% owned · share of income $1,206,535 · share of assets $26,716,800 · controlled entity
Directly controlled by CATALYST4 INC
Provenance
- Return type
- form_990
- Tax year
- 2024
- Filed
- 10 November 2025
- IRS schema version
- 2024v5.2
- Source object
- 202543159349304074
Check it against the return as filed: the GivingTuesday Data Lake hosts a public copy of the original XML.
The source document this was parsed from is served over the API, which is where bulk and document access live.