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Nonprofiteer
← CHAN ZUCKERBERG BIOHUB INC

Form 990 for tax year 2022

Filed by CHAN ZUCKERBERG BIOHUB INC.

Totals

Total revenue
$16,409,981
Total expenses
$90,813,707
Contributions and grants received
$14,330,487
Grants paid
$29,060,304
Program service revenue
$750,912
Investment income
$891,383
Other revenue
$437,199
Total assets, end of year
$271,112,430
Total liabilities, end of year
$18,118,468
Net assets or fund balances, end of year
$252,993,962
Program services expenses (Part IX)
$78,383,863
Management and general expenses
$12,429,844
Fundraising expenses
$0
Program service expenses (Part III)
$78,383,863

Program services were 86.3% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

Line items

Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.

Revenue

Part VIII, the statement of revenue.

  • 1d · Related organizations

    $5,000,000

  • 1f · All other contributions, gifts and grants

    $9,330,487

  • 1g · Noncash contributions included above

    $883,433

  • 2a · Program service revenue: COLLAB PROG.& LICENSE

    total $750,912 · related or exempt $750,912

  • 3 · Investment income

    total $891,383 · excluded $891,383

  • 5 · Royalties

    total $437,199 · excluded $437,199

Functional expenses

Part IX, the statement of functional expenses.

  • 1 · Grants to domestic organizations and governments

    total $29,060,304 · program services $29,060,304

  • 5 · Compensation of officers, directors and key employees

    total $6,293,643 · program services $3,333,262 · management and general $2,960,381

  • 7 · Other salaries and wages

    total $18,710,170 · program services $15,484,774 · management and general $3,225,396

  • 8 · Pension plan contributions

    total $918,138 · program services $759,863 · management and general $158,275

  • 9 · Other employee benefits

    total $2,610,612 · program services $2,149,437 · management and general $461,175

  • 10 · Payroll taxes

    total $1,505,542 · program services $1,133,081 · management and general $372,461

  • 11b · Fees: legal

    total $3,047,033 · program services $1,430,610 · management and general $1,616,423

  • 11c · Fees: accounting

    total $229,643 · management and general $229,643

  • 11g · Fees: other

    total $3,775,919 · program services $2,714,896 · management and general $1,061,023

  • 12 · Advertising and promotion

    total $23,757 · program services $1,035 · management and general $22,722

  • 13 · Office expenses

    total $2,201,774 · program services $2,015,235 · management and general $186,539

  • 14 · Information technology

    total $2,116,374 · program services $1,668,928 · management and general $447,446

  • 16 · Occupancy

    total $7,262,555 · program services $6,214,865 · management and general $1,047,690

  • 17 · Travel

    total $632,189 · program services $480,136 · management and general $152,053

  • 19 · Conferences, conventions and meetings

    total $821,080 · program services $799,496 · management and general $21,584

  • 20 · Interest

    total $6,200 · management and general $6,200

  • 22 · Depreciation, depletion and amortization

    total $4,459,322 · program services $4,258,935 · management and general $200,387

  • 23 · Insurance

    total $263,512 · program services $100,176 · management and general $163,336

  • 24a · Other expenses: LAB SUPPLIES

    total $6,113,936 · program services $6,113,936

  • 24b · Other expenses: MEALS & ENTERTAINMENT

    total $681,631 · program services $587,988 · management and general $93,643

  • 24c · Other expenses: ALL OTHER EXPENSES

    total $75,687 · program services $75,329 · management and general $358

  • 24d · Other expenses: LICENSES & REGISTRATION

    total $4,686 · program services $1,577 · management and general $3,109

Balance sheet

Part X, book values.

  • 1 · Cash, non-interest-bearing

    beginning of year $6,047,322 · end of year $8,211,743

  • 2 · Savings and temporary cash investments

    beginning of year $76,954,003 · end of year $83,819,723

  • 3 · Pledges and grants receivable

    beginning of year $238,971,849 · end of year $155,925,884

  • 4 · Accounts receivable

    beginning of year $531,565 · end of year $495,864

  • 9 · Prepaid expenses and deferred charges

    beginning of year $1,255,732 · end of year $1,492,771

  • 10a · Land, buildings and equipment: cost or other basis

    $28,583,156

  • 10b · Land, buildings and equipment: accumulated depreciation

    $17,601,490

  • 10c · Land, buildings and equipment, net

    beginning of year $11,929,442 · end of year $10,981,666

  • 13 · Investments: program-related

    beginning of year $974,922 · end of year $1,134,735

  • 15 · Other assets

    beginning of year $1,652,084 · end of year $9,050,044

  • 17 · Accounts payable and accrued expenses

    beginning of year $3,800,062 · end of year $3,039,831

  • 18 · Grants payable

    beginning of year $7,119,169 · end of year $6,696,071

  • 25 · Other liabilities

    beginning of year $0 · end of year $8,382,566

  • 27 · Net assets without donor restrictions

    beginning of year $84,094,121 · end of year $91,156,531

  • 28 · Net assets with donor restrictions

    beginning of year $243,303,567 · end of year $161,837,431

Mission and programs · 2022

Mission

ALLEVIATING HUMAN SUFFERING THROUGH ITS MISSION TO CURE, MANAGE, AND PREVENT ALL DISEASES BY THE END OF THE 21ST CENTURY.

Activities or mission (Part I)

CONDUCT CUTTING EDGE MEDICAL RESEARCH

  • IN 2022 THE CHAN ZUCKERBERG BIOHUB, INC. ("CZ BIOHUB") CELEBRATED ITS 6TH ANNIVERSARY AS A MEDICAL RESEARCH ORGANIZATION. CONSISTENT WITH OUR MISSION, WE CONTINUED TO FOCUS ON LARGE-SCALE SCIENTIFIC INITIATIVES THAT WE ARE UNIQUELY POSITIONED TO SUPPORT AND EXECUTE, EACH ON A MULTI-YEAR TIMELINE:1. INTRAMURAL RESEARCH PROJECTS LED BY CZ BIOHUB RESEARCHERS THAT EMPHASIZE BASIC SCIENCE, IN TWO MAIN AREAS:A. QUANTITATIVE CELL SCIENCEB. INFECTIOUS DISEASE2. PROGRAMS SUPPORTING SCIENTISTS AND PHYSICIANS AT OUR INSTITUTIONS UNIVERSITIES (STANFORD UNIVERSITY; UC SAN FRANCISCO; UC BERKELEY) THROUGH THE CZ BIOHUB INVESTIGATOR PROGRAM, PHYSICIAN-SCIENTIST FELLOWSHIP PROGRAM, AND COLLABORATIVE POSTDOCTORAL FELLOWSHIP PROGRAM.HIGHLIGHTS- IN MARCH 2022, THE PAPER DESCRIBING OPENCELL - AN OPEN-SOURCE, PROTEOME-SCALE COLLECTION OF PROTEIN LOCALIZATION AND INTERACTION MEASUREMENTS IN HUMAN CELLS - WAS PUBLISHED IN SCIENCE, AND HAS SINCE BEEN DOWNLOADED MORE THAN 31,000 TIMES. THE OPENCELL'S ALTMETRIC SCORE IS 433, PLACING IT IN THE TOP 5% OF ALL RESEARCH OUTPUTS TRACKED BY ALTMETRIC. FOR THIS ACHIEVEMENT AND HIS LARGER BODY OF WORK, CZ BIOHUB SF SCIENTIST MANUEL LEONETTI WON THE INNOVATION IN RESEARCH AWARD FROM THE AMERICAN SOCIETY FOR CELL BIOLOGY, A DISTINCTION THAT "RECOGNIZES EARLY AND MID-CAREER SCIENTISTS FOR THEIR NEW AND INNOVATIVE RESEARCH IN CELL BIOLOGY."- THE TABULA SAPIENS, A SINGLE-CELL ATLAS OF MORE THAN 400 HUMAN CELL TYPES BASED ON ANALYSIS OF NEARLY 500,000 CELLS FROM MULTIPLE ORGANS, WAS PUBLISHED IN SCIENCE IN MAY 2022. THE PAPER HAS SINCE BEEN DOWNLOADED NEARLY 120,000 TIMES, AND HAS AN ALTMETRIC SCORE OF 1158, PLACING IT IN THE TOP 5% OF ALL RESEARCH OUTPUTS TRACKED BY ALTMETRIC.- OUR RAPID RESPONSE TEAM TRAINED VISITING SCIENTIFIC TEAMS FROM ZAMBIA, PAKISTAN, CAMBODIA, AND BANGLADESH IN METAGENOMIC NEXT-GENERATION SEQUENCING TECHNIQUES AND THE USE OF CZ ID, AN OPEN-SOURCE WEB PORTAL AND DATABASE TO TRACK AND IDENTIFY PATHOGENS IN THEIR RESPECTIVE COUNTRIES AND RESPOND TO INFECTIOUS DISEASE OUTBREAKS.- IN JANUARY 2022, WE ANNOUNCED OUR SECOND COHORT OF CZ BIOHUB INVESTIGATORS, 86 SCIENTISTS WORKING IN DIVERSE FIELDS AT STANFORD, UCSF, AND UC BERKELEY SUPPORTED BY UNRESTRICTED RESEARCH GRANTS FROM THE BIOHUB.- THROUGH OUR COLLABORATIVE POSTDOCTORAL FELLOWSHIP PROGRAM, WE SUPPORTED INTERDISCIPLINARY, COLLABORATIVE RESEARCH BY SEVEN FELLOWS IN LABS AT ALL THREE OF OUR PARTNER UNIVERSITIES. OUR PHYSICIAN-SCIENTIST FELLOWSHIP PROGRAM TRAINED SIX PHYSICIANS AT UCSF AND STANFORD UNIVERSITY IN BIOMEDICAL RESEARCH TECHNIQUES (BOTH LABORATORY AND COMPUTATIONAL) THROUGH AN IMMERSIVE, HANDS-ON EXPERIENCE.

    Expenses $78,383,863 · Grants $29,060,304 · Revenue $750,912

As filed on the 2022 return. The filer continues this part on Schedule O, which is not shown here.

Listed in Part VII

  • JOSEPH DERISI

    CO-PRESIDENT & DIRECTOR

    Total calculated
    $888,042
    From this org
    $848,528
    From related orgs
    $0
    Other
    $39,514
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $581,391
    Bonus
    $265,205
    Other
    $1,932
    Deferred
    $14,971
    Nontaxable benefits
    $24,543
    Filer's total
    $888,042

  • STEVE QUAKE

    CO-PRESIDENT & DIRECTOR

    Total calculated
    $612,598
    From this org
    $581,077
    From related orgs
    $0
    Other
    $31,521
    Hours/week
    10

    Schedule J breakdown matched by us

    Base
    $405,945
    Bonus
    $174,085
    Other
    $1,047
    Deferred
    $13,504
    Nontaxable benefits
    $18,017
    Filer's total
    $612,598

  • CORI BARGMANN

    DIRECTOR

    Total calculated
    $0
    Hours/week
    3

  • JOHN HENNESSY

    DIRECTOR

    Total calculated
    $0
    Hours/week
    3

  • MARK ZUCKERBERG

    DIRECTOR

    Total calculated
    $0
    Hours/week
    3 + 41 related

  • PRISCILLA CHAN

    DIRECTOR

    Total calculated
    $0
    Hours/week
    3 + 4 related

  • REID HOFFMAN

    DIRECTOR

    Total calculated
    $0
    Hours/week
    3

  • VICTOR COLUNGA

    CFO & TREASURER

    Total calculated
    $767,120
    From this org
    $723,474
    From related orgs
    $0
    Other
    $43,646
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $471,459
    Bonus
    $241,200
    Other
    $10,815
    Deferred
    $13,500
    Nontaxable benefits
    $30,146
    Filer's total
    $767,120

  • MELINDA GRIFFITH START 522

    CHIEF LEGAL OFFICER & SECRETARY

    Total calculated
    $507,772
    From this org
    $482,716
    From related orgs
    $0
    Other
    $25,056
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $314,584
    Bonus
    $161,020
    Other
    $7,112
    Deferred
    $12,936
    Nontaxable benefits
    $12,120
    Filer's total
    $507,772

  • GAJUS WORTHINGTON END 122

    CHIEF OPERATING OFFICER

    Total calculated
    $46,958
    From this org
    $37,931
    From related orgs
    $0
    Other
    $9,027
    Hours/week
    40

  • SANDRA L SCHMID

    CHIEF SCIENTIFIC OFFICER

    Total calculated
    $756,117
    From this org
    $726,183
    From related orgs
    $0
    Other
    $29,934
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $479,439
    Bonus
    $241,200
    Other
    $5,544
    Deferred
    $18,328
    Nontaxable benefits
    $11,606
    Filer's total
    $756,117

  • SONYA ZILKA

    CHIEF PEOPLE OFFICER

    Total calculated
    $647,938
    From this org
    $625,730
    From related orgs
    $0
    Other
    $22,208
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $412,438
    Bonus
    $208,450
    Other
    $4,842
    Deferred
    $13,500
    Nontaxable benefits
    $8,708
    Filer's total
    $647,938

  • ROSIO ALVAREZ

    CHIEF INFORMATION OFFICER

    Total calculated
    $642,346
    From this org
    $611,991
    From related orgs
    $0
    Other
    $30,355
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $403,269
    Bonus
    $203,550
    Other
    $5,172
    Deferred
    $15,421
    Nontaxable benefits
    $14,934
    Filer's total
    $642,346

  • JIM KARKANIAS END 1222

    CHIEF TECHNOLOGY OFFICER

    Total calculated
    $606,378
    From this org
    $568,378
    From related orgs
    $0
    Other
    $38,000
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $379,714
    Bonus
    $185,200
    Other
    $3,464
    Deferred
    $13,577
    Nontaxable benefits
    $24,423
    Filer's total
    $606,378

  • AMY E HERR START 222

    CHIEF TECHNOLOGY OFFICER, CZ BIOHUB NETWORK

    Total calculated
    $491,533
    From this org
    $479,085
    From related orgs
    $0
    Other
    $12,448
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $317,745
    Bonus
    $160,342
    Other
    $998
    Deferred
    $9,929
    Nontaxable benefits
    $2,519
    Filer's total
    $491,533

  • MANDANA ASGHAMEJAD 722-1122

    CHIEF OPERATING OFFICER

    Total calculated
    $350,070
    From this org
    $335,578
    From related orgs
    $0
    Other
    $14,492
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $145,782
    Bonus
    $300
    Other
    $189,496
    Deferred
    $6,092
    Nontaxable benefits
    $8,400
    Filer's total
    $350,070

  • WILLIAM BURKHOLDER

    DIRECTOR, SCIENTIFIC PROGRAM MANAGEMENT

    Total calculated
    $317,135
    From this org
    $272,971
    From related orgs
    $0
    Other
    $44,164
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $233,713
    Bonus
    $37,050
    Other
    $2,208
    Deferred
    $13,998
    Nontaxable benefits
    $30,166
    Filer's total
    $317,135

  • CRAIG KAPFER

    SENIOR DIRECTOR, SCIENTIFIC COMPUTING

    Total calculated
    $375,221
    From this org
    $347,093
    From related orgs
    $0
    Other
    $28,128
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $277,550
    Bonus
    $58,600
    Other
    $10,943
    Deferred
    $9,722
    Nontaxable benefits
    $18,406
    Filer's total
    $375,221

  • RAFAEL GOMEZ-SJOBERG

    SR. DIRECTOR, BIOENGINEERING

    Total calculated
    $368,867
    From this org
    $324,412
    From related orgs
    $0
    Other
    $44,455
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $264,877
    Bonus
    $58,100
    Other
    $1,435
    Deferred
    $13,500
    Nontaxable benefits
    $30,955
    Filer's total
    $368,867

  • ANNETTE PARENT

    LEAD IP COUNSEL

    Total calculated
    $365,433
    From this org
    $337,828
    From related orgs
    $0
    Other
    $27,605
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $276,589
    Bonus
    $57,200
    Other
    $4,039
    Deferred
    $13,388
    Nontaxable benefits
    $14,217
    Filer's total
    $365,433

  • ASTRID HO

    CONTROLLER

    Total calculated
    $320,206
    From this org
    $271,937
    From related orgs
    $0
    Other
    $48,269
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $228,963
    Bonus
    $42,200
    Other
    $774
    Deferred
    $10,250
    Nontaxable benefits
    $38,019
    Filer's total
    $320,206

  • CRISTINA TATO

    DIRECTOR, RAPID RESPONSE TEAM

    Total calculated
    $278,755
    From this org
    $263,535
    From related orgs
    $0
    Other
    $15,220
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $220,503
    Bonus
    $38,350
    Other
    $4,682
    Deferred
    $11,900
    Nontaxable benefits
    $3,320
    Filer's total
    $278,755

Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us.

Schedule J

Answered yes

  • 3 · Independent compensation consultant
  • 3 · Compensation survey or study
  • 3 · Approval by the board or compensation committee
  • 4a · Severance or change-of-control payment
  • 7 · Other non-fixed payments

Answered no

  • 4b · Supplemental nonqualified retirement plan
  • 4c · Equity-based compensation arrangement
  • 5a · Pay contingent on this organization's revenues
  • 5b · Pay contingent on a related organization's revenues
  • 6a · Pay contingent on this organization's net earnings
  • 6b · Pay contingent on a related organization's net earnings
  • 8 · Paid under the initial-contract exception

The filer's explanations (Part III)

PART I, LINE 4A
DURING 2022, THE ORGANIZATION PAID SEVERANCE TO THE FOLLOWING INDIVIDUALS: MANDANA ASGHAMEJAD - $187,648. JIM KARKANIAS PARTICIPATED IN A SEPARATION AGREEMENT THAT WAS EXECUTED AND EFFECTIVE AS OF 12/31/22.
PART I, LINE 7
INCENTIVE COMPENSATION WAS PROVIDED TO CERTAIN PERSONS LISTED ON PART VII OF THE FORM 990. INCENTIVE COMPENSATION WAS PAID BASED ON A FIXED PERCENTAGE OF BASE COMPENSATION, PLUS AN ADDITIONAL DISCRETIONARY PERCENTAGE SUBJECT TO BOARD APPROVAL.

Part I's answers as filed. A line not listed was left unanswered; on lines 1a and 3 that means the box was not checked.

Grants on this return

Related organizations on this return

Schedule R Part II: tax-exempt organizations related to the filer by control. It does not record shared board members or money.

Taxable family on this return

Schedule R Parts I, III and IV, as filed. These record ownership and control, not shared board members or money moved.

Disregarded entities

Part I: entities that legally are the filer and file no return of their own.

  • CZ BIOHUB SF LLC

    MEDICAL RESEARCH · CA · income $0 · assets $0

    Directly controlled by CHAN ZUCKERBERG BIOHUB INC

Related corporations and trusts

Part IV: related organizations taxable as a corporation or trust.

Provenance

Return type
form_990
Tax year
2022
Filed
14 November 2023
IRS schema version
2022v5.0
Source object
202303189349301730

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