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← ALTERNATIVES FOR RESEARCH AND DEVELOPMENT FOUNDATION

Form 990 for tax year 2025

Filed by ALTERNATIVES FOR RESEARCH AND DEVELOPMENT FOUNDATION.

Totals

Total revenue
$1,391,661
Total expenses
$947,409
Contributions and grants received
$79,690
Grants paid
$432,731
Program service revenue
$0
Investment income
$1,311,971
Other revenue
$0
Total assets, end of year
$17,124,006
Total liabilities, end of year
$105,402
Net assets or fund balances, end of year
$17,018,604
Program services expenses (Part IX)
$751,037
Management and general expenses
$188,943
Fundraising expenses
$7,429
Program service expenses (Part III)
$751,037

Program services were 79.3% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

Line items

Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.

Revenue

Part VIII, the statement of revenue.

  • 1f · All other contributions, gifts and grants

    $79,690

  • 3 · Investment income

    total $285,586 · excluded $285,586

  • 7a · Gross sales of assets other than inventory

    securities $3,476,058

  • 7b · Less cost or other basis and sales expenses

    securities $2,449,673

  • 7c · Gain or loss

    securities $1,026,385

  • 7d · Net gain or loss

    total $1,026,385 · excluded $1,026,385

Functional expenses

Part IX, the statement of functional expenses.

  • 1 · Grants to domestic organizations and governments

    total $332,731 · program services $332,731

  • 3 · Grants to foreign organizations and individuals

    total $100,000 · program services $100,000

  • 5 · Compensation of officers, directors and key employees

    total $20,000 · program services $20,000

  • 7 · Other salaries and wages

    total $28,305 · program services $9,621 · management and general $13,211 · fundraising $5,473

  • 9 · Other employee benefits

    total $9,901 · program services $4,639 · management and general $3,883 · fundraising $1,379

  • 10 · Payroll taxes

    total $2,876 · program services $1,324 · management and general $1,101 · fundraising $451

  • 11b · Fees: legal

    total $108 · management and general $108

  • 11c · Fees: accounting

    total $18,735 · management and general $18,735

  • 11f · Fees: investment management

    total $147,723 · management and general $147,723

  • 11g · Fees: other

    total $215,641 · program services $215,195 · management and general $393 · fundraising $53

  • 13 · Office expenses

    total $12,241 · program services $9,137 · management and general $3,031 · fundraising $73

  • 16 · Occupancy

    total $19,548 · program services $18,890 · management and general $658

  • 19 · Conferences, conventions and meetings

    total $33,957 · program services $33,957

  • 22 · Depreciation, depletion and amortization

    total $600 · program services $600

  • 23 · Insurance

    total $79 · program services $59 · management and general $20

  • 24a · Other expenses: RESEARCH AND INFORMATIO

    total $4,739 · program services $4,706 · management and general $33

  • 24b · Other expenses: POSTAGE AND SHIPPING

    total $225 · program services $178 · management and general $47

Balance sheet

Part X, book values.

  • 1 · Cash, non-interest-bearing

    beginning of year $46,218 · end of year $25,065

  • 2 · Savings and temporary cash investments

    beginning of year $2,260,339 · end of year $2,298,163

  • 4 · Accounts receivable

    beginning of year $18,069 · end of year $18,069

  • 9 · Prepaid expenses and deferred charges

    beginning of year $3,250 · end of year $3,250

  • 10a · Land, buildings and equipment: cost or other basis

    $12,396

  • 10b · Land, buildings and equipment: accumulated depreciation

    $12,096

  • 10c · Land, buildings and equipment, net

    beginning of year $900 · end of year $300

  • 11 · Investments: publicly traded securities

    beginning of year $14,050,290 · end of year $14,287,793

  • 15 · Other assets

    beginning of year $469,610 · end of year $491,366

  • 17 · Accounts payable and accrued expenses

    beginning of year $3,677 · end of year $5,642

  • 25 · Other liabilities

    beginning of year $40,460 · end of year $99,760

  • 27 · Net assets without donor restrictions

    beginning of year $14,624,283 · end of year $14,738,597

  • 28 · Net assets with donor restrictions

    beginning of year $2,180,256 · end of year $2,280,007

Mission and programs · 2025

Mission

THE MISSION OF THE ARDF IS TO FUND AND PROMOTE THE DEVELOPMENT, VALIDATION AND ADOPTION OF NON-ANIMAL METHODS IN BIOMEDICAL RESEARCH, PRODUCT TESTING, AND EDUCATION.

Activities or mission (Part I)

ARDF PROMOTES AND DEVELOPS ALTERNATIVE SCIENTIFIC SOLUTIONS TO THE PROBLEM OF ANIMAL TESTING.

  • THE "ANNUAL OPEN" GRANT PROGRAM FUNDS INNOVATIVE NON-ANIMAL METHODS TO REDUCE OR REPLACE ANIMAL USE IN RESEARCH AND TESTINGIN 2025, ARDF FUNDED THE FOLLOWING PROJECTS FOR SCIENTIFIC RESEARCH: 1) ENGINEERED HUMAN HEART MODELS FOR ADVANCING DRUG CARDIAC SAFETY ASSESSMENT; 2) IN VITRO MODELLING OF BUBBLE-ASSISTED FOCUSED ULTRASOUND BLOOD-BRAIN BARRIER OPENING; 3) AN ADVANCED EX VIVO MODEL FOR IDIOPATHIC PULMONARY FIBROSIS; 4) REPLACING ANIMAL-DERIVED PRODUCTS IN DRUG DEVELOPMENT IN VITRO MODELS; 5) IMMUNE DISRUPTORS AND THE DEVELOPING BRAIN: UNRAVELING HOW IMMUNOTOXICANTS SHAPE NEURODEVELOPMENT; 6) ADVANCING ORGANOID INTELLIGENCE WITH A HIPPOCAMPAL-CORTICAL SYSTEM; 7) GENERATION OF THE OLFACTORY EPITHELIUM FROM HUMAN PLURIPOTENT STEM CELLS TO STUDY NEURODEGENERATION; AND 8) A HUMAN-RELEVANT MODEL FOR REAL-TIME MONITORING OF MYCN-DRIVEN NEUROBLASTOMA SPREADING AND DRUG TESTING. THESE PROJECTS REFLECT ARDF'S CONTINUED EMPHASIS ON SUPPORTING HUMAN-RELEVANT, ANIMAL-FREE APPROACHES FOR BIOMEDICAL RESEARCH AND DRUG DEVELOPMENT, INCLUDING CELL- AND TISSUE-BASED SYSTEMS, ORGANOID AND STEM CELL TECHNOLOGIES, COMPUTATIONALLY INFORMED MODELS, AND OTHER ADVANCED IN VITRO AND EX VIVO METHODS. BY SUPPORTING RESEARCH TO DEVELOP AND ADVANCE ALTERNATIVE, ANIMAL-FREE MODELS, ARDF CONTINUES TO PROMOTE BOTH ANIMAL WELFARE AND HUMAN HEALTH. ARDF ALSO CONTINUED DEVELOPMENT OF ITS ALTERNATIVES IN RESEARCH CHALLENGE, A DISEASE-FOCUSED GRANT INITIATIVE SUPPORTING NON-ANIMAL APPROACHES TO CHILDHOOD CANCER RESEARCH. ARDF ALSO CONTRIBUTES ITS EXPERTISE TO SCIENTIFIC AND POLICY DISCUSSIONS CONCERNING THE ADVANCEMENT, VALIDATION, AND ADOPTION OF NON-ANIMAL METHODS. IN 2025, ARDF SUPPORTED EDUCATION, OUTREACH, AND SCIENTIFIC EXCHANGE TO ACCELERATE UNDERSTANDING OF HUMAN-RELEVANT APPROACHES AND TO FOSTER COLLABORATION AMONG RESEARCHERS, POLICYMAKERS, AND OTHER STAKEHOLDERS.

    Expenses $751,037 · Grants $432,731

As filed on the 2025 return. The filer continues this part on Schedule O, which is not shown here.

Listed in Part VII

  • SUE LEARY

    PRESIDENT (PRIOR TO 10/7/25)

    Total calculated
    $58,791
    From this org
    $15,462
    From related orgs
    $41,090
    Other
    $2,239
    Hours/week
    12 + 35 related

  • LUKE KLEIN

    PRESIDENT (AFTER 10/7/25)

    Total calculated
    $126,016
    From this org
    $4,538
    From related orgs
    $105,685
    Other
    $15,793
    Hours/week
    12 + 35 related

  • NADIA S ADAWI

    BOARD MEMBER

    Total calculated
    $0
    Hours/week
    0.5 + 0.5 related

  • ROBERT FINN

    BOARD MEMBER

    Total calculated
    $0
    Hours/week
    0.5 + 0.5 related

  • EILEEN SMITH

    BOARD MEMBER

    Total calculated
    $0
    Hours/week
    0.5 + 0.5 related

  • JOSEPH LUDWIG

    VICE PRESIDENT

    Total calculated
    $0
    Hours/week
    0.5 + 1 related

  • AARON MCINTYRE

    TREASURER

    Total calculated
    $0
    Hours/week
    0.5 + 1 related

  • DENISE COWIE

    SECRETARY

    Total calculated
    $0
    Hours/week
    0.5 + 1 related

Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those.

Grants on this return

Related organizations on this return

Schedule R Part II: tax-exempt organizations related to the filer by control. It does not record shared board members or money.

Provenance

Return type
form_990
Tax year
2025
Filed
11 May 2026
IRS schema version
2025v4.1
Source object
202611349349308821

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