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Nonprofiteer
← CANCER PREVENTION INITIATIVE INC

Form 990 for tax year 2023

Filed by CANCER PREVENTION INITIATIVE INC.

Totals

Total revenue
$49,585
Total expenses
$74,394
Contributions and grants received
$65
Grants paid
$53,367
Program service revenue
$0
Investment income
$49,520
Other revenue
$0
Total assets, end of year
$821,212
Total liabilities, end of year
$145,996
Net assets or fund balances, end of year
$675,216
Program services expenses (Part IX)
$59,049
Management and general expenses
$15,345
Fundraising expenses
$0
Program service expenses (Part III)
$59,049

Program services were 79.4% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

Line items

Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.

Revenue

Part VIII, the statement of revenue.

  • 1a · Federated campaigns

    $0

  • 1b · Membership dues

    $0

  • 1c · Fundraising events

    $0

  • 1d · Related organizations

    $0

  • 1e · Government grants (contributions)

    $0

  • 1f · All other contributions, gifts and grants

    $65

  • 1g · Noncash contributions included above

    $0

  • 3 · Investment income

    total $49,520 · related or exempt $0 · unrelated business $0 · excluded $49,520

  • 4 · Income from investment of tax-exempt bond proceeds

    total $0 · related or exempt $0 · unrelated business $0 · excluded $0

  • 5 · Royalties

    total $0 · related or exempt $0 · unrelated business $0 · excluded $0

  • 6c · Rental income or loss

    real property $0 · personal property $0

  • 7c · Gain or loss

    securities $0 · other assets $0

  • 8a · Fundraising events: contributions included on line 1c

    $0

  • 11e · Other revenue, total

    $0

Functional expenses

Part IX, the statement of functional expenses.

  • 1 · Grants to domestic organizations and governments

    total $53,367 · program services $53,367

  • 2 · Grants to domestic individuals

    total $0 · program services $0

  • 3 · Grants to foreign organizations and individuals

    total $0 · program services $0

  • 11c · Fees: accounting

    total $2,845 · management and general $2,845

  • 13 · Office expenses

    total $4,430 · program services $0 · management and general $4,430

  • 14 · Information technology

    total $6,002 · program services $5,682 · management and general $320

  • 22 · Depreciation, depletion and amortization

    total $3,590 · management and general $3,590

  • 23 · Insurance

    total $2,586 · management and general $2,586

  • 24a · Other expenses: Bank Charges

    total -$25 · program services $0 · management and general -$25 · fundraising $0

  • 24b · Other expenses: Fees & Licenses

    total $1,599 · program services $0 · management and general $1,599 · fundraising $0

Balance sheet

Part X, book values.

  • 1 · Cash, non-interest-bearing

    beginning of year $1,165 · end of year $6,759

  • 2 · Savings and temporary cash investments

    beginning of year $14,413 · end of year $3,826

  • 3 · Pledges and grants receivable

    beginning of year $0 · end of year $0

  • 4 · Accounts receivable

    beginning of year $0 · end of year $0

  • 5 · Loans and receivables from officers and key people

    beginning of year $0 · end of year $0

  • 6 · Loans and receivables from disqualified persons

    beginning of year $0 · end of year $0

  • 7 · Other notes and loans receivable

    beginning of year $0 · end of year $0

  • 8 · Inventories for sale or use

    beginning of year $0 · end of year $0

  • 9 · Prepaid expenses and deferred charges

    beginning of year $6,676 · end of year $1,012

  • 11 · Investments: publicly traded securities

    beginning of year $1,025,357 · end of year $804,620

  • 12 · Investments: other securities

    beginning of year $0

  • 13 · Investments: program-related

    beginning of year $0

  • 14 · Intangible assets

    beginning of year $8,585 · end of year $4,995

  • 15 · Other assets

    beginning of year $0

  • 17 · Accounts payable and accrued expenses

    beginning of year $93 · end of year $955

  • 18 · Grants payable

    beginning of year $356,078 · end of year $145,000

  • 19 · Deferred revenue

    beginning of year $0 · end of year $0

  • 20 · Tax-exempt bond liabilities

    beginning of year $0 · end of year $0

  • 21 · Escrow or custodial account liability

    beginning of year $0 · end of year $0

  • 22 · Loans and payables to officers and key people

    beginning of year $0 · end of year $0

  • 23 · Secured mortgages and notes payable

    beginning of year $0 · end of year $0

  • 24 · Unsecured notes and loans payable

    beginning of year $0

  • 25 · Other liabilities

    end of year $41

  • 27 · Net assets without donor restrictions

    beginning of year $235,261 · end of year $263,818

  • 28 · Net assets with donor restrictions

    beginning of year $464,764 · end of year $411,398

Mission and programs · 2023

Mission

Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer. CPI uses its research, medical and pharmaceutical expertise to invest in first-rate science that will discover new strategies for preventing cancer. Our strategy is to support research on prevention of inherited cancers as a path towards elimination of all cancers. CPI acts as a facilitator to ensure that good ideas can find sufficient funding to turn them into therapeutic solutions such as drugs or vaccines to prevent cancer. CPI provides financial support, guidance and expertise throughout the research and development process to help researchers use the resources (donations) for the highest possible impact.

Activities or mission (Part I)

Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer.

  • In 2023, Cancer Prevention Initiative (CPI) opened an application cycle to identify new projects to fund. We accepted proposals pertaining to the therapeutic prevention of any inherited cancer, as we wish to expand our research portfolio beyond BRCA1/2 mutated cancers to all inherited cancers. We received applications covering all three strategic categories of research: Discovery research that expands the knowledge of early-pre-cancer stages and mechanisms of cancer initiation, development of early detection tests, and the development of chemo and/or immunotherapeutic agents. The response exceeded our expectations, with a total of 79 applications received. This volume indicates both the need for funding in this area and the enthusiasm of the research community to invest their discovery efforts in prevention. Also in 2023, CPI's ongoing research grant recipients have advanced towards greater understanding of preventing inherited cancers. Ongoing projects include Cleveland Clinic, where investigators seek to identify proteins uniquely and highly expressed in breast cancer of BRCA1 mutation carriers. Identification of these unique proteins is an important link for developing preventative vaccines. Also continuing is a project with Memorial Sloan Kettering Cancer Center to generate a robust cellular assay that would allow for the screening of hundreds of compounds to identify determinants of Loss of Heterozygosity (LoH) of BRCA genes. LoH is a major driver in cancer initiation, and discovery of compounds that cause LoH can be key for prevention discoveries. Other ongoing projects include Harvard's Beth Israel Deaconess Medical Center where they are working to identify cancer risk predictors in the reproductive epithelium in BRCA mutation carriers, and work at the University of Toronto to screen for drugs that can restore normal BRCA1 function to BRCA1 deficient cells.

    Expenses $53,367 · Grants $53,367

  • Education and engagement programs: As we move closer to our goal of eradicating all cancers through preventative medicines, we believe that educating the public and raising awareness about inherited cancer syndromes will inspire more individuals to take proactive, life-saving preventive measures. One of the goals is to enhance the scientific reach of the organization and raise awareness on cancer prevention to a broader audience of patients, advocates and donors. Updates on scientific and medical research advances, recent clinical trials, and interviews with experts in cancer prevention are published on web-based platforms.

    Expenses $5,682

As filed on the 2023 return.

Listed in Part VII

  • Theodora Ross

    President & Chief Scientific Officer

    Total calculated
    $0
    Hours/week
    10

  • Howard Janzen

    Board Chair; Chief Financial Officer

    Total calculated
    $0
    Hours/week
    3

  • Kirk Patrick

    Secretary, Trustee

    Total calculated
    $0
    Hours/week
    0.5

  • Jan Livingston-Mokhtari

    Trustee

    Total calculated
    $0
    Hours/week
    0.5

  • Douglas Hager

    Trustee, Sr. Vice President, Project Management and Operations

    Total calculated
    $0
    Hours/week
    10

  • Joi Morris

    Trustee

    Total calculated
    $0
    Hours/week
    5

Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those.

Grants on this return

Provenance

Return type
form_990
Tax year
2023
Filed
13 May 2024
IRS schema version
2023v5.0
Source object
202411349349303976

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