- Revenue 2024
- $31,755,677
- Expenses 2024
- $36,999,068
Program services were 91.3% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.
As filed
- Subsection
- 03
- NTEE code
- H83
- Classification
- 2000
- Street
- 34 WASHINGTON ST STE 230
These codes are the IRS's own and are shown exactly as filed. What each one means is in the Business Master File documentation (opens in a new tab).
Officers and directors · 2024
As listed in Part VII of the 2024 return, in the order the filer printed them. Each return names its own; this is not a roster the organization keeps with us.
-
MARGARET E SMITH
CEO
- Total calculated
- $455,433
- From this org
- $426,320
- From related orgs
- $0
- Other
- $29,113
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $407,378
- Bonus
- $18,942
- Other
- $0
- Deferred
- $10,350
- Nontaxable benefits
- $18,763
- Filer's total
- $455,433
-
HENRY MCCANCE
CHAIR
- Total calculated
- $0
- Hours/week
- 5
-
PHYLLIS RAPPAPORT
TREASURER
- Total calculated
- $0
- Hours/week
- 5
-
TIMOTHY ARMOUR
DIRECTOR
- Total calculated
- $0
- Hours/week
- 3
-
RICHARD BIRNBAUM
DIRECTOR
- Total calculated
- $0
- Hours/week
- 4
-
MARK FAGGIANO
DIRECTOR (FROM 10/24)
- Total calculated
- $0
- Hours/week
- 3
-
MARY GREENHILL CAGLIERO
DIRECTOR (FROM 10/24)
- Total calculated
- $0
- Hours/week
- 3
-
ROBERT GREENHILL
DIRECTOR (TO 10/24)
- Total calculated
- $0
- Hours/week
- 3
-
KUMAR MAHADEVA
DIRECTOR (FROM 12/24)
- Total calculated
- $0
- Hours/week
- 3
-
JACQUELINE MORBY
DIRECTOR
- Total calculated
- $0
- Hours/week
- 4
-
JOSEPHINE ANTONELLIS
CFO
- Total calculated
- $207,441
- From this org
- $200,226
- From related orgs
- $0
- Other
- $7,215
- Hours/week
- 30
Schedule J breakdown matched by us
- Base
- $190,226
- Bonus
- $10,000
- Other
- $0
- Deferred
- $6,014
- Nontaxable benefits
- $1,201
- Filer's total
- $207,441
-
LAUREL LYLE
SECRETARY & VP BOARD RELATIONS & DEV OPS
- Total calculated
- $125,326
- From this org
- $121,094
- From related orgs
- $0
- Other
- $4,232
- Hours/week
- 30
-
KATHARINE HERMAN
EVP DEVELOPMENT
- Total calculated
- $448,817
- From this org
- $418,581
- From related orgs
- $0
- Other
- $30,236
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $342,381
- Bonus
- $76,200
- Other
- $0
- Deferred
- $10,350
- Nontaxable benefits
- $19,886
- Filer's total
- $448,817
-
JULIE HARRIS
EVP RESEARCH MGMT (TO 12/24)
- Total calculated
- $306,210
- From this org
- $296,359
- From related orgs
- $0
- Other
- $9,851
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $276,634
- Bonus
- $19,725
- Other
- $0
- Deferred
- $8,891
- Nontaxable benefits
- $960
- Filer's total
- $306,210
-
BARBARA CHAMBERS
EVP MARKETING & COMM.
- Total calculated
- $290,642
- From this org
- $267,548
- From related orgs
- $0
- Other
- $23,094
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $246,348
- Bonus
- $21,200
- Other
- $0
- Deferred
- $8,403
- Nontaxable benefits
- $14,691
- Filer's total
- $290,642
-
LISA RAND
VP MARKETING & COMM.
- Total calculated
- $217,835
- From this org
- $199,320
- From related orgs
- $0
- Other
- $18,515
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $194,120
- Bonus
- $5,200
- Other
- $0
- Deferred
- $6,268
- Nontaxable benefits
- $12,247
- Filer's total
- $217,835
-
DANIEL HARPER
VP DEVELOPMENT
- Total calculated
- $208,193
- From this org
- $195,493
- From related orgs
- $0
- Other
- $12,700
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $189,293
- Bonus
- $6,200
- Other
- $0
- Deferred
- $5,959
- Nontaxable benefits
- $6,741
- Filer's total
- $208,193
-
JOHN SLATTERY
SVP, PHILANTHROPIC PARTNERSHIPS
- Total calculated
- $205,775
- From this org
- $198,792
- From related orgs
- $0
- Other
- $6,983
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $189,592
- Bonus
- $9,200
- Other
- $0
- Deferred
- $6,054
- Nontaxable benefits
- $929
- Filer's total
- $205,775
-
MAHUA DASGUPTA
SR. PHILANTROPIC ADVISOR
- Total calculated
- $203,654
- From this org
- $178,255
- From related orgs
- $0
- Other
- $25,399
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $172,055
- Bonus
- $6,200
- Other
- $0
- Deferred
- $5,690
- Nontaxable benefits
- $19,709
- Filer's total
- $203,654
-
THIDAPHORN SENGSAVANH
DIRECTOR OF DEVELOPMENT OPS
- Total calculated
- $178,296
- From this org
- $154,055
- From related orgs
- $0
- Other
- $24,241
- Hours/week
- 40
Schedule J breakdown matched by us
- Base
- $146,855
- Bonus
- $7,200
- Other
- $0
- Deferred
- $4,883
- Nontaxable benefits
- $19,358
- Filer's total
- $178,296
Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us. Earlier years are each on their own filing page.
Filings
-
2024
- Revenue
- $31,755,677
- Expenses
- $36,999,068
- Contributions
- $30,788,755
- Grants paid
- $28,828,950
-
2023
- Revenue
- $37,725,207
- Expenses
- $34,633,548
- Contributions
- $36,697,205
- Grants paid
- $26,431,117
-
2022
- Revenue
- $40,708,245
- Expenses
- $30,613,014
- Contributions
- $32,354,655
- Grants paid
- $23,431,727
The four totals the IRS asks for on Part I of the Form 990, as filed. A dash means the figure was not present on the return — not that it was zero.
Grants made
-
MASSACHUSETTS GENERAL HOSPITAL
$1,955,000
2022 THECUREALZALZHEIMERS GENOME PROJECT
-
MASSACHUSETTS GENERAL HOSPITAL
$1,955,000
2023 THE CUREALZ ALZHEIMER'S GENOME PROJECT
-
MASSACHUSETTS GENERAL HOSPITAL
$1,955,000
2024 THE CUREALZ ALZHEIMER'S GENOME PROJECT
-
$575,000
2024 APOE: APOE4 ACCELERATES CD8 EXHAUSTION VIA GLUCOCORTICOID SIGNALING IN ALZHEIMER'S FEMALE CARRIERS
-
$431,250
2023 A NEW MODEL OF MICROGLIA GENETIC PERTURBATION IN VIVO TO SCREEN ALL RISK FACTORS ASSOCIATED WITH ALZHEIMER'S DISEASE
-
2024 SEX-BIASED TLR7 SIGNALING IN DEMYELINATION AND ITS INHIBITION BY SMALL MOLECULES
-
$345,000
2022 BEE: CROSSTALK OF CNS BARRIERS AND CLEARANCE ROUTES IN HOMEOSTASIS AND ALZHEIMERS DISEASE
-
$345,000
2023 MBC: INTERACTION OF THE MICROBIOME WITH ASTROCYTES AND AMYLOID PATHOLOGY
-
$345,000
2022 APOE CONSORTIUM: ROLE OF APOE ISOFORMS IN IMMUNE RESPONSES IN A MODEL OF TAUOPATHY
-
MASSACHUSETTS GENERAL HOSPITAL
$345,000
2023 NEUROPROTECTIVE EFFECTS OF THE EXERCISE HORMONE IRISIN IN ALZHEIMER'S DISEASE
The 10 largest by cash amount. The API serves every itemized grant.
Grants received
-
FIDELITY INVESTMENTS CHARITABLE GIFT FUND
$2,857,239
2024 For grant recipient's exempt purposes
-
FIDELITY INVESTMENTS CHARITABLE GIFT FUND
$2,021,013
2023 For grant recipient's exempt purposes
-
$1,964,671
2023 UNRESTRICTED
-
FIDELITY INVESTMENTS CHARITABLE GIFT FUND
$1,324,253
2022 For grant recipient's exempt purposes
-
DONOR ADVISED CHARITABLE GIVING
$1,007,106
2024 HEALTH
-
DONOR ADVISED CHARITABLE GIVING
$960,967
2023 HEALTH
-
DONOR ADVISED CHARITABLE GIVING
$611,701
2022 HEALTH
-
$500,000
2024 PROVIDE GENERAL OPERATING SUPPORT
-
UNIVERSITY OF NOTRE DAME DU LAC
$500,000
2022 See Part IV
-
$474,965
2024 UNRESTRICTED
The 10 largest by cash amount. The API serves every itemized grant.
Other IRS files
Auto-Revocation List
Not listed. The IRS publishes this list for organizations whose exemption was automatically revoked for failing to file for three consecutive years.
Publication 78
Listed as of 10 September 2026, under deductibility PC.
These are two separate IRS files on two separate schedules, shown as published and not reconciled with each other. Neither is a statement about whether a contribution is deductible today: 19,245 organizations appear in Publication 78 while the IRS's own revocation file lists them as currently revoked, more than half of those revoked before 2019. Absence from Publication 78 is evidence of nothing, and presence is not evidence either. Verify current status with the IRS before relying on it.