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← INSTITUTE FOR IN VITRO SCIENCES INC

Form 990 for tax year 2025

Filed by INSTITUTE FOR IN VITRO SCIENCES INC.

Totals

Total revenue
$7,901,249
Total expenses
$7,883,164
Contributions and grants received
$793,498
Grants paid
$0
Program service revenue
$7,069,056
Investment income
$5,626
Other revenue
$33,069
Total assets, end of year
$5,555,372
Total liabilities, end of year
$3,178,014
Net assets or fund balances, end of year
$2,377,358
Program services expenses (Part IX)
$7,399,857
Management and general expenses
$462,888
Fundraising expenses
$20,419
Program service expenses (Part III)
$7,399,857

Program services were 93.9% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

Line items

Every line the filer filed in Parts VIII, IX and X, as filed and in filed order. Blank columns are left out, and the lines are not forced to add up to the totals above.

Revenue

Part VIII, the statement of revenue.

  • 1e · Government grants (contributions)

    $38,826

  • 1f · All other contributions, gifts and grants

    $754,672

  • 2a · Program service revenue: RESEARCH AND TESTING

    total $6,805,283 · related or exempt $6,805,283

  • 2b · Program service revenue: EDUCATIONAL ACTIVITIES

    total $263,773 · related or exempt $263,773

  • 3 · Investment income

    total $5,626 · excluded $5,626

  • 11a · Other revenue: REIMBURSEMENTS

    total $27,604 · excluded $27,604

  • 11b · Other revenue: REFUND

    total $5,465 · excluded $5,465

  • 11e · Other revenue, total

    $33,069

Functional expenses

Part IX, the statement of functional expenses.

  • 5 · Compensation of officers, directors and key employees

    total $354,961 · program services $255,863 · management and general $85,190 · fundraising $13,908

  • 7 · Other salaries and wages

    total $3,454,068 · program services $3,261,002 · management and general $193,066

  • 8 · Pension plan contributions

    total $103,929 · program services $101,109 · management and general $2,820

  • 9 · Other employee benefits

    total $354,273 · program services $338,970 · management and general $14,920 · fundraising $383

  • 10 · Payroll taxes

    total $287,808 · program services $272,173 · management and general $14,866 · fundraising $769

  • 11b · Fees: legal

    total $7,215 · management and general $7,215

  • 11c · Fees: accounting

    total $58,919 · management and general $58,919

  • 11g · Fees: other

    total $211,116 · program services $210,965 · management and general $143 · fundraising $8

  • 12 · Advertising and promotion

    total $30,416 · program services $30,416

  • 13 · Office expenses

    total $51,849 · program services $50,088 · management and general $1,660 · fundraising $101

  • 14 · Information technology

    total $226,463 · program services $207,205 · management and general $18,850 · fundraising $408

  • 15 · Royalties

    total $1,953 · program services $1,953

  • 16 · Occupancy

    total $546,566 · program services $516,886 · management and general $28,223 · fundraising $1,457

  • 17 · Travel

    total $169,703 · program services $165,316 · management and general $3,160 · fundraising $1,227

  • 19 · Conferences, conventions and meetings

    total $16,312 · program services $15,758 · management and general $554

  • 20 · Interest

    total $12,392 · program services $11,975 · management and general $396 · fundraising $21

  • 22 · Depreciation, depletion and amortization

    total $234,005 · program services $223,063 · management and general $10,401 · fundraising $541

  • 23 · Insurance

    total $95,943 · program services $77,931 · management and general $17,791 · fundraising $221

  • 24a · Other expenses: LABORATORY EXPENSES

    total $1,647,390 · program services $1,647,390

  • 24b · Other expenses: DUES/MEMBERSHIPS/PUBS.

    total $12,210 · program services $11,601 · management and general $609

  • 24c · Other expenses: PENALTIES & FINES

    total $4,105 · management and general $4,105

  • 24d · Other expenses: LICENSE FEES & PERMITS

    total $1,568 · program services $193 · fundraising $1,375

Balance sheet

Part X, book values.

  • 1 · Cash, non-interest-bearing

    beginning of year $71,138 · end of year $65,201

  • 2 · Savings and temporary cash investments

    beginning of year $648,096 · end of year $613,203

  • 3 · Pledges and grants receivable

    beginning of year $107,162 · end of year $255,346

  • 4 · Accounts receivable

    beginning of year $1,851,300 · end of year $1,953,690

  • 9 · Prepaid expenses and deferred charges

    beginning of year $126,073 · end of year $137,054

  • 10a · Land, buildings and equipment: cost or other basis

    $2,535,985

  • 10b · Land, buildings and equipment: accumulated depreciation

    $1,823,694

  • 10c · Land, buildings and equipment, net

    beginning of year $872,411 · end of year $712,291

  • 15 · Other assets

    beginning of year $2,249,573 · end of year $1,818,587

  • 17 · Accounts payable and accrued expenses

    beginning of year $570,660 · end of year $605,953

  • 19 · Deferred revenue

    beginning of year $215,975 · end of year $303,135

  • 23 · Secured mortgages and notes payable

    beginning of year $161,716 · end of year $125,556

  • 25 · Other liabilities

    beginning of year $2,618,129 · end of year $2,143,370

  • 27 · Net assets without donor restrictions

    beginning of year $2,334,273 · end of year $2,333,200

  • 28 · Net assets with donor restrictions

    beginning of year $25,000 · end of year $44,158

Mission and programs · 2025

Mission

THE MISSION OF THE INSTITUTE FOR IN VITRO SCIENCES (IIVS) IS TO DRIVE THE OPTIMIZATION AND APPLICATION OF SCIENTIFICALLY ROBUST IN VITRO METHODS THAT ARE ACCEPTED BY REGULATORY AGENCIES AND ADOPTED BY INDUSTRY WORLDWIDE. TO CREATE A FORUM IN WHICH INDUSTRY, REGULATORY AGENCIES AND ANIMAL WELFARE ORGANIZATIONS CAN WORK TOGETHER TO DEVELOP HUMANE SCIENTIFIC TOOLS FOR TESTING. TO UTILIZE OUR EXPERTISE TO CREATE EDUCATIONAL AND OUTREACH PROGRAMS THAT WILL EXPAND THE ADOPTION OF NON-ANIMAL TEST METHODS AROUND THE GLOBE.

Activities or mission (Part I)

TO INCREASE THE USE AND ACCEPTANCE OF NON-ANIMAL TEST METHODS WORLDWIDE.

  • RESEARCH AND TESTING: IIVS WORKED WITH MORE THAN SIXTY COMPANIES TO DETERMINE THE APPROPRIATE NON-ANIMAL TESTING STRATEGIES, CONDUCT TESTING, AND ASSIST IN INTERPRETATION OF DATA. OVER 880 COMPOUNDS/PRODUCTS WERE TESTED AT THE IIVS LABORATORY - MOSTLY IN MORE THAN ONE TEST. IIVS CONTINUES TO OPTIMIZE AND STANDARDIZE IN VITRO METHODS TO MAKE THEM SUITABLE FOR INDUSTRY AND REGULATORY NEEDS. MANY OF THESE EFFORTS ARE IN COLLABORATION WITH STAKEHOLDERS SUCH AS INDUSTRY, GOVERNMENT AND NGOS. ADVANCEMENTS ARE SHARED WITH THE SCIENTIFIC COMMUNITY THROUGH PRESENTATIONS AND PUBLICATIONS SO THAT OTHER INDUSTRIES AND REGULATORY SCIENTISTS CAN BENEFIT. IIVS HAS DEVELOPED AND PROMOTED THE USE OF HUMAN PRECISION CUT LUNG SLICES (HPCLS) FOR POTENTIAL REGULATORY APPLICATION AS AN ALTERNATIVE TO USING ANIMALS FOR INHALATION AND RESPIRATORY ENDPOINTS. BASED UPON OUR SUCCESSFUL USE OF HPCLS IN IN-HOUSE STUDIES, STAKEHOLDERS HAVE INQUIRED WHETHER THEY COULD PROCURE THESE HPCLS TISSUES FOR USE WITHIN THEIR OWN LABORATORIES. IIVS PREPARED AND QUALIFIED HPCLS TISSUES FOR 30 SPONSOR-RUN LABORATORY STUDIES THAT WOULD HAVE OTHERWISE USED ANIMALS.

    Expenses $6,332,999 · Revenue $6,805,283

  • EDUCATION AND OUTREACH: IIVS PARTICIPATES IN NUMEROUS TRAINING ACTIVITIES FOR A VARIETY OF STAKEHOLDERS INCLUDING INDUSTRY AND REGULATORY SCIENTISTS. THESE TRAININGS ARE TAILORED FOR THE SPECIFIC AUDIENCE AND GENERALLY INCLUDE LECTURES, HANDS-ON DEMONSTRATIONS AND DATA INTERPRETATION. TWO MAJOR PROGRAMS IN WHICH IIVS PARTICIPATES ARE THE PHYSICIANS COMMITTEE FOR RESPONSIBLE MEDICINE NURA TRAINING AND THE ANIMAL FREE SAFETY ASSESSMENT COLLABORATION COORDINATED BY HUMANE SOCIETY INTERNATIONAL. IIVS SCIENTISTS WERE INVITED TO PARTICIPATE IN EXPERT PANELS CONVENED BY THE ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT (OECD) WHICH HARMONIZES IN VITRO TESTING APPROACHES FOR THE WORLDWIDE SCIENTIFIC COMMUNITY. THESE PANELS DISCUSSED NEW METHODS FOR GENETIC TOXICOLOGY, SKIN SENSITIZATION, EYE IRRITATION AND SKIN CORROSION. IIVS IS LEADING EFFORTS WITH INDUSTRY CONSORTIA AND 2 DIVISIONS OF THE U.S. FEDERAL DRUG ADMINISTRATION TO APPLY NON-ANIMAL METHODS FOR SPECIFIC ENDPOINTS. IIVS IS ALSO INVOLVED IN EFFORTS TO SUPPORT THE U.S. ENVIRONMENTAL PROTECTION AGENCY'S GOAL TO REDUCE RELIANCE ON ANIMAL MODELS. IIVS STAFF HOLD BOARD POSITIONS WITHIN SOCIETIES THAT HAVE THE MISSION TO WORK COLLABORATIVELY TO INCREASE THE USE AND ACCEPTANCE OF ALTERNATIVE METHODS, SUCH AS THE AMERICAN SOCIETY FOR CELLULAR AND COMPUTATIONAL TOXICOLOGY, THE EUROPEAN SOCIETY OF TOXICOLOGY IN VITRO, THE U.S. SOCIETY OF TOXICOLOGY AND THE CHINESE SOCIETY OF TOXICOLOGY.

    Expenses $1,066,858 · Revenue $263,773

As filed on the 2025 return. The filer continues this part on Schedule O, which is not shown here.

Listed in Part VII

  • Amanda K Ulrey

    PRESIDENT

    Total calculated
    $167,797
    From this org
    $160,387
    From related orgs
    $0
    Other
    $7,410
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $160,387
    Bonus
    $0
    Other
    $0
    Deferred
    $6,408
    Nontaxable benefits
    $1,002
    Filer's total
    $167,797

  • Hans A Raabe

    CHIEF OPERATING OFFICER/TREASURER

    Total calculated
    $172,796
    From this org
    $152,576
    From related orgs
    $0
    Other
    $20,220
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $152,576
    Bonus
    $0
    Other
    $0
    Deferred
    $6,577
    Nontaxable benefits
    $13,643
    Filer's total
    $172,796

  • Rodger D Curren

    CEO/BOARD CHAIR/SECRETARY

    Total calculated
    $14,368
    From this org
    $13,815
    From related orgs
    $0
    Other
    $553
    Hours/week
    10

  • Daniel A Bagley

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • John R Fowle

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • A Wallace Hayes

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • James M Hoffman

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • Richard E Kouri

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • Holger P Behrsing

    DIRECTOR RESPIRATORY TOXICOLOGY

    Total calculated
    $181,262
    From this org
    $165,396
    From related orgs
    $0
    Other
    $15,866
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $165,396
    Bonus
    $0
    Other
    $0
    Deferred
    $6,590
    Nontaxable benefits
    $9,276
    Filer's total
    $181,262

  • Gertrude-Emilia Costin

    DIRECTOR OF LABORATORY SERVICES

    Total calculated
    $165,543
    From this org
    $153,460
    From related orgs
    $0
    Other
    $12,083
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $153,460
    Bonus
    $0
    Other
    $0
    Deferred
    $0
    Nontaxable benefits
    $12,083
    Filer's total
    $165,543

  • Allison M Hilberer

    TOXICOLOGIST II/STUDY DIRECTOR

    Total calculated
    $136,837
    From this org
    $123,067
    From related orgs
    $0
    Other
    $13,770
    Hours/week
    40

  • Nathan R Wilt

    STUDY DIRECTOR

    Total calculated
    $135,109
    From this org
    $121,135
    From related orgs
    $0
    Other
    $13,974
    Hours/week
    40

  • Kristie M Sullivan

    VP, EDUCATION AND OUTREACH

    Total calculated
    $123,055
    From this org
    $117,318
    From related orgs
    $0
    Other
    $5,737
    Hours/week
    40

Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us.

Schedule J

Answered yes

  • 3 · Form 990 of other organizations
  • 3 · Compensation survey or study
  • 3 · Approval by the board or compensation committee

Answered no

  • 4a · Severance or change-of-control payment
  • 4b · Supplemental nonqualified retirement plan
  • 4c · Equity-based compensation arrangement
  • 5a · Pay contingent on this organization's revenues
  • 5b · Pay contingent on a related organization's revenues
  • 6a · Pay contingent on this organization's net earnings
  • 6b · Pay contingent on a related organization's net earnings
  • 7 · Other non-fixed payments
  • 8 · Paid under the initial-contract exception

Part I's answers as filed. A line not listed was left unanswered; on lines 1a and 3 that means the box was not checked.

Grants on this return

No itemized grants to organizations on this return.

Provenance

Return type
form_990
Tax year
2025
Filed
6 August 2026
IRS schema version
2025v4.2
Source object
202642189349301704

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