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INSTITUTE FOR IN VITRO SCIENCES INC

EIN 52-2029668 GAITHERSBURG, MD

Browse the largest nonprofits in Maryland

Revenue 2025
$7,901,249
Expenses 2025
$7,883,164

Program services were 93.9% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

As filed

Subsection
03
NTEE code
B28
Classification
8400
Street
30 W WATKINS MILL RD STE 100

These codes are the IRS's own and are shown exactly as filed. What each one means is in the Business Master File documentation (opens in a new tab).

Other organizations at this address

1 other organization in the IRS Business Master File lists the same street address. matched by us

This address is a suite or unit (STE 100). Organizations that share one are often clients of the same office-services firm, accountant or registered agent rather than related to each other.

We match the street line and ZIP code as the IRS gives them, ignoring case and outer spaces and nothing else, so "AVE" and "AVENUE" count as different streets and this list can miss some. A shared address can mean related organizations or a shared office, but it can also be a registered agent, a mail drop or a service provider holding mail for unrelated clients. It is not, by itself, evidence that two organizations are connected.

Mission and programs · 2025

Mission

THE MISSION OF THE INSTITUTE FOR IN VITRO SCIENCES (IIVS) IS TO DRIVE THE OPTIMIZATION AND APPLICATION OF SCIENTIFICALLY ROBUST IN VITRO METHODS THAT ARE ACCEPTED BY REGULATORY AGENCIES AND ADOPTED BY INDUSTRY WORLDWIDE. TO CREATE A FORUM IN WHICH INDUSTRY, REGULATORY AGENCIES AND ANIMAL WELFARE ORGANIZATIONS CAN WORK TOGETHER TO DEVELOP HUMANE SCIENTIFIC TOOLS FOR TESTING. TO UTILIZE OUR EXPERTISE TO CREATE EDUCATIONAL AND OUTREACH PROGRAMS THAT WILL EXPAND THE ADOPTION OF NON-ANIMAL TEST METHODS AROUND THE GLOBE.

Activities or mission (Part I)

TO INCREASE THE USE AND ACCEPTANCE OF NON-ANIMAL TEST METHODS WORLDWIDE.

  • RESEARCH AND TESTING: IIVS WORKED WITH MORE THAN SIXTY COMPANIES TO DETERMINE THE APPROPRIATE NON-ANIMAL TESTING STRATEGIES, CONDUCT TESTING, AND ASSIST IN INTERPRETATION OF DATA. OVER 880 COMPOUNDS/PRODUCTS WERE TESTED AT THE IIVS LABORATORY - MOSTLY IN MORE THAN ONE TEST. IIVS CONTINUES TO OPTIMIZE AND STANDARDIZE IN VITRO METHODS TO MAKE THEM SUITABLE FOR INDUSTRY AND REGULATORY NEEDS. MANY OF THESE EFFORTS ARE IN COLLABORATION WITH STAKEHOLDERS SUCH AS INDUSTRY, GOVERNMENT AND NGOS. ADVANCEMENTS ARE SHARED WITH THE SCIENTIFIC COMMUNITY THROUGH PRESENTATIONS AND PUBLICATIONS SO THAT OTHER INDUSTRIES AND REGULATORY SCIENTISTS CAN BENEFIT. IIVS HAS DEVELOPED AND PROMOTED THE USE OF HUMAN PRECISION CUT LUNG SLICES (HPCLS) FOR POTENTIAL REGULATORY APPLICATION AS AN ALTERNATIVE TO USING ANIMALS FOR INHALATION AND RESPIRATORY ENDPOINTS. BASED UPON OUR SUCCESSFUL USE OF HPCLS IN IN-HOUSE STUDIES, STAKEHOLDERS HAVE INQUIRED WHETHER THEY COULD PROCURE THESE HPCLS TISSUES FOR USE WITHIN THEIR OWN LABORATORIES. IIVS PREPARED AND QUALIFIED HPCLS TISSUES FOR 30 SPONSOR-RUN LABORATORY STUDIES THAT WOULD HAVE OTHERWISE USED ANIMALS.

    Expenses $6,332,999 · Revenue $6,805,283

  • EDUCATION AND OUTREACH: IIVS PARTICIPATES IN NUMEROUS TRAINING ACTIVITIES FOR A VARIETY OF STAKEHOLDERS INCLUDING INDUSTRY AND REGULATORY SCIENTISTS. THESE TRAININGS ARE TAILORED FOR THE SPECIFIC AUDIENCE AND GENERALLY INCLUDE LECTURES, HANDS-ON DEMONSTRATIONS AND DATA INTERPRETATION. TWO MAJOR PROGRAMS IN WHICH IIVS PARTICIPATES ARE THE PHYSICIANS COMMITTEE FOR RESPONSIBLE MEDICINE NURA TRAINING AND THE ANIMAL FREE SAFETY ASSESSMENT COLLABORATION COORDINATED BY HUMANE SOCIETY INTERNATIONAL. IIVS SCIENTISTS WERE INVITED TO PARTICIPATE IN EXPERT PANELS CONVENED BY THE ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT (OECD) WHICH HARMONIZES IN VITRO TESTING APPROACHES FOR THE WORLDWIDE SCIENTIFIC COMMUNITY. THESE PANELS DISCUSSED NEW METHODS FOR GENETIC TOXICOLOGY, SKIN SENSITIZATION, EYE IRRITATION AND SKIN CORROSION. IIVS IS LEADING EFFORTS WITH INDUSTRY CONSORTIA AND 2 DIVISIONS OF THE U.S. FEDERAL DRUG ADMINISTRATION TO APPLY NON-ANIMAL METHODS FOR SPECIFIC ENDPOINTS. IIVS IS ALSO INVOLVED IN EFFORTS TO SUPPORT THE U.S. ENVIRONMENTAL PROTECTION AGENCY'S GOAL TO REDUCE RELIANCE ON ANIMAL MODELS. IIVS STAFF HOLD BOARD POSITIONS WITHIN SOCIETIES THAT HAVE THE MISSION TO WORK COLLABORATIVELY TO INCREASE THE USE AND ACCEPTANCE OF ALTERNATIVE METHODS, SUCH AS THE AMERICAN SOCIETY FOR CELLULAR AND COMPUTATIONAL TOXICOLOGY, THE EUROPEAN SOCIETY OF TOXICOLOGY IN VITRO, THE U.S. SOCIETY OF TOXICOLOGY AND THE CHINESE SOCIETY OF TOXICOLOGY.

    Expenses $1,066,858 · Revenue $263,773

As filed on the 2025 return. The filer continues this part on Schedule O, which is not shown here.

Officers and directors · 2025

As listed in Part VII of the 2025 return, in the order the filer printed them. Each return names its own; this is not a roster the organization keeps with us.

  • Amanda K Ulrey

    PRESIDENT

    Total calculated
    $167,797
    From this org
    $160,387
    From related orgs
    $0
    Other
    $7,410
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $160,387
    Bonus
    $0
    Other
    $0
    Deferred
    $6,408
    Nontaxable benefits
    $1,002
    Filer's total
    $167,797
  • Hans A Raabe

    CHIEF OPERATING OFFICER/TREASURER

    Total calculated
    $172,796
    From this org
    $152,576
    From related orgs
    $0
    Other
    $20,220
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $152,576
    Bonus
    $0
    Other
    $0
    Deferred
    $6,577
    Nontaxable benefits
    $13,643
    Filer's total
    $172,796
  • Rodger D Curren

    CEO/BOARD CHAIR/SECRETARY

    Total calculated
    $14,368
    From this org
    $13,815
    From related orgs
    $0
    Other
    $553
    Hours/week
    10
  • Daniel A Bagley

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5
  • John R Fowle

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5
  • A Wallace Hayes

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5
  • James M Hoffman

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5
  • Richard E Kouri

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5
  • Holger P Behrsing

    DIRECTOR RESPIRATORY TOXICOLOGY

    Total calculated
    $181,262
    From this org
    $165,396
    From related orgs
    $0
    Other
    $15,866
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $165,396
    Bonus
    $0
    Other
    $0
    Deferred
    $6,590
    Nontaxable benefits
    $9,276
    Filer's total
    $181,262
  • Gertrude-Emilia Costin

    DIRECTOR OF LABORATORY SERVICES

    Total calculated
    $165,543
    From this org
    $153,460
    From related orgs
    $0
    Other
    $12,083
    Hours/week
    40

    Schedule J breakdown matched by us

    Base
    $153,460
    Bonus
    $0
    Other
    $0
    Deferred
    $0
    Nontaxable benefits
    $12,083
    Filer's total
    $165,543
  • Allison M Hilberer

    TOXICOLOGIST II/STUDY DIRECTOR

    Total calculated
    $136,837
    From this org
    $123,067
    From related orgs
    $0
    Other
    $13,770
    Hours/week
    40
  • Nathan R Wilt

    STUDY DIRECTOR

    Total calculated
    $135,109
    From this org
    $121,135
    From related orgs
    $0
    Other
    $13,974
    Hours/week
    40
  • Kristie M Sullivan

    VP, EDUCATION AND OUTREACH

    Total calculated
    $123,055
    From this org
    $117,318
    From related orgs
    $0
    Other
    $5,737
    Hours/week
    40

Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us. Earlier years are each on their own filing page.

Filings

  • 2025
    Revenue
    $7,901,249
    Expenses
    $7,883,164
    Contributions
    $793,498
    Grants paid
    $0
  • 2024
    Revenue
    $7,953,184
    Expenses
    $7,935,798
    Contributions
    $841,058
    Grants paid
    $0
  • 2023
    Revenue
    $6,877,981
    Expenses
    $7,165,636
    Contributions
    $1,057,602
    Grants paid
    $0
  • 2022
    Revenue
    $6,860,766
    Expenses
    $6,922,486
    Contributions
    $1,077,048
    Grants paid
    $500

The four totals the IRS asks for on Part I of the Form 990, as filed. A dash means the figure was not present on the return — not that it was zero.

Other returns filed

  • 2021 · 990

    Revenue
    $6,503,470
    Expenses
    $6,070,350
    Assets (EOY)
    $4,102,375
  • 2020 · 990

    Revenue
    $5,879,153
    Expenses
    $5,698,595
    Assets (EOY)
    $4,281,216
  • 2019 · 990

    Revenue
    $5,519,690
    Expenses
    $5,897,856
    Assets (EOY)
    $3,490,495
  • 2018 · 990

    Revenue
    $5,484,946
    Expenses
    $5,192,081
    Assets (EOY)
    $2,966,766
  • 2017 · 990

    Revenue
    $4,450,537
    Expenses
    $4,525,308
    Assets (EOY)
    $2,686,320
  • 2016 · 990

    Revenue
    $4,398,140
    Expenses
    $4,632,356
    Assets (EOY)
    $2,443,012
  • 2015 · 990

    Revenue
    $3,955,985
    Expenses
    $4,220,450
    Assets (EOY)
    $2,717,439
  • 2014 · 990

    Revenue
    $4,237,425
    Expenses
    $4,172,709
    Assets (EOY)
    $2,996,435
  • 2013 · 990

    Revenue
    $3,935,387
    Expenses
    $3,400,201
    Assets (EOY)
    $2,881,382
  • 2012 · 990

    Revenue
    not reported
    Expenses
    $3,144,533
    Assets (EOY)
    $2,310,598

Nonprofiteer parses Forms 990, 990-EZ and 990-PF, in a window of recent tax years. These returns are recorded from the IRS e-file index, so their figures were extracted by that index rather than read from the return here — treat them as a different source from the filings above, not as more of the same record. A dash means the index carries no figure; Form 990-T listings carry none at all. Showing the 10 most recent; the API carries the rest.

Grants made

No itemized grants to organizations. Schedule I is filed only by organizations that granted more than $5,000 to a recipient, so most filers have none.

Grants received

Other IRS files

Auto-Revocation List

Not listed. The IRS publishes this list for organizations whose exemption was automatically revoked for failing to file for three consecutive years.

Publication 78

Listed as of 11 November 2026, under deductibility PC.

These are two separate IRS files on two separate schedules, shown as published and not reconciled with each other. Neither is a statement about whether a contribution is deductible today: 19,245 organizations appear in Publication 78 while the IRS's own revocation file lists them as currently revoked, more than half of those revoked before 2019. Absence from Publication 78 is evidence of nothing, and presence is not evidence either. Verify current status with the IRS before relying on it.

What this page reflects

The registration facts above come from the IRS Business Master File published 9 November 2026 and read 9 November 2026, for every organization at once. Returns through tax year 2025, the newest we have parsed for this organization.