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ST JUDE CHILDRENS RESEARCH HOSPITAL INC

EIN 62-0646012 MEMPHIS, TN

Browse the largest nonprofits in Tennessee

Revenue 2024
$2,208,853,162
Expenses 2024
$1,897,571,834

Program services were 92.5% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

As filed

Subsection
03
NTEE code
E240
Classification
1200
Street
262 DANNY THOMAS PL

These codes are the IRS's own and are shown exactly as filed. What each one means is in the Business Master File documentation (opens in a new tab).

Mission and programs · 2024

Mission

THE MISSION OF ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS TO ADVANCE CURES, AND MEANS OF PREVENTION, FOR PEDIATRIC CATASTROPHIC DISEASES THROUGH RESEARCH AND TREATMENT. CONSISTENT WITH THE VISION OF OUR FOUNDER DANNY THOMAS, NO CHILD IS DENIED (CONTINUED ON SCHEDULE O) TREATMENT BASED ON RACE, RELIGION OR A FAMILY'S ABILITY TO PAY.

Activities or mission (Part I)

THE MISSION OF ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS TO ADVANCE CURES, AND MEANS OF PREVENTION, FOR PEDIATRIC CATASTROPHIC DISEASES THROUGH RESEARCH AND TREATMENT. CONSISTENT WITH THE VISION OF OUR FOUNDER DANNY THOMAS, NO CHILD IS DENIED TREATMENT BASED ON RACE, RELIGION OR A FAMILY'S ABILITY TO PAY.

  • RESEARCH: THE CURRENT BASIC SCIENCE AND CLINICAL RESEARCH AT THE HOSPITAL INCLUDES WORK IN GENE THERAPY, CHEMOTHERAPY, THE BIOCHEMISTRY OF NORMAL AND CANCEROUS CELLS, RADIATION TREATMENT, BLOOD DISEASES, RESISTANCE TO THERAPY, VIRUSES, NEUROLOGICAL DISEASES, HEREDITARY DISEASES, INFLUENZA, PEDIATRIC AIDS AND PHYSIOLOGICAL EFFECTS OF CATASTROPHIC ILLNESSES.

    Expenses $883,215,145 · Grants $178,680 · Revenue $3,020

  • PATIENT CARE: THE HOSPITAL PROVIDED 17,927 INPATIENT DAYS OF CARE DURING THE YEAR. OUR BONE MARROW TRANSPLANTATION PROGRAM ACCOUNTED FOR 3,805 OR 21% OF THOSE INPATIENT DAYS. PATIENTS MADE 74,651 CLINIC REGISTRATIONS DURING THE YEAR.

    Expenses $726,650,059 · Grants $3,636,000 · Revenue $143,039,289

  • EDUCATION AND TRAINING: AS PART OF ITS MISSION, THE INSTITUTION HAS DEVELOPED A GLOBAL INITIATIVE (ST. JUDE GLOBAL) TO IMPROVE THE SURVIVAL RATES OF CHILDREN WITH CANCER AND OTHER CATASTROPHIC DISEASES WORLDWIDE. ST. JUDE GLOBAL ACCOMPLISHES THIS BY SHARING KNOWLEDGE, TECHNOLOGY AND ORGANIZATIONAL SKILLS, HELPING TO IMPLEMENT NEW APPROACHES TO TREAT PEDIATRIC CANCER GLOBALLY, AND DEVELOPING REGIONAL NETWORKS COMMITTED TO ERADICATING CANCER IN CHILDREN. THIS MISSION WILL BE ACHIEVED BY FOCUSING ON THREE OVERRIDING GOALS: (1) TO TRAIN THE CLINICAL WORKFORCE THAT WILL BE REQUIRED TO MEET OUR MISSION, (2) TO DEVELOP AND STRENGTHEN HEALTH SYSTEMS AND PATIENT-CENTERED INITIATIVES THAT ENCOMPASS THE ENTIRE CONTINUUM OF CARE REQUIRED FOR CHILDREN WITH CANCER AND NON-MALIGNANT HEMATOLOGICAL (CONTINUED ON SCHEDULE O) DISEASES, AND (3) TO ADVANCE KNOWLEDGE IN GLOBAL PEDIATRIC ONCOLOGY AND HEMATOLOGY THROUGH RESEARCH TO SUSTAIN A CONTINUOUS IMPROVEMENT IN THE LEVEL AND QUALITY OF CARE DELIVERED AROUND THE GLOBE. THESE INITIATIVES ARE SPEARHEADED BY ST. JUDE EXPERTS WHO WORK CLOSELY WITH HEALTHCARE PROFESSIONALS AT OUR PARTNER SITES.THE GLOBAL INITIATIVE FOR CHILDHOOD CANCER, LAUNCHED IN 2018 BY ST. JUDE IN PARTNERSHIP WITH WHO AND GLOBAL COLLABORATORS, AIMS TO ADDRESS DISPARITIES IN CHILDHOOD CANCER OUTCOMESWHERE SURVIVAL IS BELOW 30% IN MANY LOW AND MIDDLE INCOME COUNTRIES COMPARED TO OVER 80% IN HIGH INCOME SETTINGS. THE INITIATIVE SEEKS TO RAISE GLOBAL SURVIVAL TO AT LEAST 60% BY 2030 BY STRENGTHENING COUNTRIES' ABILITY TO DELIVER QUALITY CANCER CARE AND ELEVATING CHILDHOOD CANCER AS A NATIONAL AND INTERNATIONAL HEALTH PRIORITY. STAKEHOLDERS ACROSS SECTORS ARE WORKING TOGETHER TO IMPROVE ACCESS, CAPACITY, AND COORDINATED ACTION FOR CHILDREN WITH CANCER WORLDWIDE.THE GLOBAL PLATFORM FOR ACCESS TO CHILDHOOD CANCER MEDICINES IS A MAJOR EFFORT LED BY ST. JUDE TO ENSURE LIFESAVING CANCER TREATMENTS ARE AVAILABLE, ACCESSIBLE, AFFORDABLE, AND HIGH QUALITY FOR CHILDREN WORLDWIDE. BACKED BY A $200 MILLION ST. JUDE INVESTMENT AND BUILT IN PARTNERSHIP WITH WHO, UNICEF, AND PAHO, THE INITIATIVE IS RESTRUCTURING THE FRAGMENTED PEDIATRIC CANCER MEDICINE MARKET TO HELP ACHIEVE GLOBAL SURVIVAL GOALS. PILOT DELIVERIES BEGAN IN 2025, WITH ADDITIONAL COUNTRIES NOW ONBOARDING AS THE PROGRAM SCALES TOWARD REACHING 120,000 CHILDREN WITHIN THE NEXT SEVEN YEARS.GRADUATE PROGRAMS AT BOTH THE MASTER'S AND DOCTORAL LEVELS ARE OFFERED THROUGH A WHOLLY OWNED SUBSIDIARY, ST. JUDE CHILDREN'S RESEARCH HOSPITAL GRADUATE SCHOOL OF BIOMEDICAL SCIENCES, LLC, TO EDUCATE THE NEXT GENERATION OF BIOMEDICAL RESEARCHERS TO PROBE THE MOLECULAR BASIS OF DISEASE, DEVELOP NOVEL THERAPIES AND TRAIN MEDICAL PROFESSIONALS TO ADVANCE GLOBAL HEALTH FOR CHILDREN WITH CATASTROPHIC DISEASES.

    Expenses $146,234,497 · Grants $7,171,881 · Revenue $10,498

As filed on the 2024 return. The filer continues this part on Schedule O, which is not shown here.

Officers and directors · 2024

As listed in Part VII of the 2024 return, in the order the filer printed them. Each return names its own; this is not a roster the organization keeps with us.

  • James R Downing

    PRESIDENT/CEO

    Total calculated
    $1,713,883
    From this org
    $1,647,264
    From related orgs
    $0
    Other
    $66,619
    Hours/week
    55 + 1 related

    Schedule J breakdown matched by us

    Base
    $1,581,245
    Bonus
    $50,250
    Other
    $15,769
    Deferred
    $37,950
    Nontaxable benefits
    $28,669
    Filer's total
    $1,713,883
  • Richard C Shadyac Jr

    EX-OFFICIO DIRECTOR (THRU 3/25)

    Total calculated
    $1,564,611
    From this org
    $0
    From related orgs
    $1,393,252
    Other
    $171,359
    Hours/week
    1 + 55 related

    Schedule J breakdown matched by us

    Base
    $0 + $1,286,179 related
    Bonus
    $0
    Other
    $0 + $107,073 related
    Deferred
    $0 + $145,310 related
    Nontaxable benefits
    $0 + $26,049 related
    Filer's total
    $0 + $1,564,611 related
  • Joyce A Aboussie

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Steven J Allen MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Joseph S Ayoub Jr Esq

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Paul J Ayoub Esq

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    8 + 4 related
  • Frederick M Azar MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 8 related
  • Khalil Z Barrage

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Martha Perine Beard

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 8 related
  • Terry L Burman

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Lisa R Diller MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Joseph E Eid MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • John D Farina

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Fred P Gattas III Pharmd

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Gabriel G Haddad MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Judy A Habib

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    8 + 4 related
  • Charles C Hajjar

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Fouad A Hajjar MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Michael K Hamra

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Frederick R Harris Jr MD

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    8 + 4 related
  • Carla Z Hassan

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • J David Karam II

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 8 related
  • Scott A Kupor

    VOTING DIRECTOR (THRU 4/25)

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Katherine N Lapp

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related
  • Sharon L McCollam

    VOTING DIRECTOR

    Total calculated
    $0
    Hours/week
    4 + 4 related

The first 25 listed. Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead, and on a Form 990-PF Part VIII's — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us. Earlier years are each on their own filing page.

Filings

  • 2024
    Revenue
    $2,208,853,162
    Expenses
    $1,897,571,834
    Contributions
    $2,040,469,420
    Grants paid
    $10,986,561
  • 2023
    Revenue
    $2,009,853,917
    Expenses
    $1,772,678,423
    Contributions
    $1,840,997,693
    Grants paid
    $5,299,920
  • 2022
    Revenue
    $1,707,244,071
    Expenses
    $1,519,049,173
    Contributions
    $1,514,862,066
    Grants paid
    $12,884,704

The four totals the IRS asks for on Part I of the Form 990, as filed. A dash means the figure was not present on the return — not that it was zero.

Other returns filed

  • 2021 · 990

    Revenue
    $1,385,684,376
    Expenses
    $1,278,569,778
    Assets (EOY)
    $9,470,257,087
  • 2020 · 990

    Revenue
    $1,272,197,039
    Expenses
    $1,166,556,148
    Assets (EOY)
    $9,161,722,368
  • 2019 · 990

    Revenue
    $1,238,182,174
    Expenses
    $1,103,980,537
    Assets (EOY)
    $6,740,895,238
  • 2018 · 990

    Revenue
    $1,107,969,131
    Expenses
    $1,021,442,301
    Assets (EOY)
    $6,214,238,431
  • 2017 · 990

    Revenue
    $980,656,319
    Expenses
    $950,715,632
    Assets (EOY)
    $5,434,170,902
  • 2017 · 990

    Revenue
    $980,656,319
    Expenses
    $950,715,632
    Assets (EOY)
    $5,434,170,902
  • 2016 · 990

    Revenue
    $900,801,934
    Expenses
    $857,021,844
    Assets (EOY)
    $4,787,635,534
  • 2015 · 990

    Revenue
    $1,027,517,864
    Expenses
    $797,219,240
    Assets (EOY)
    $4,292,347,585
  • 2014 · 990

    Revenue
    $794,815,526
    Expenses
    $753,684,867
    Assets (EOY)
    $4,080,012,224
  • 2013 · 990

    Revenue
    $740,730,972
    Expenses
    $683,276,029
    Assets (EOY)
    $3,880,303,145

Nonprofiteer parses Forms 990, 990-EZ and 990-PF, in a window of recent tax years. These returns are recorded from the IRS e-file index, so their figures were extracted by that index rather than read from the return here — treat them as a different source from the filings above, not as more of the same record. A dash means the index carries no figure; Form 990-T listings carry none at all. Showing the 10 most recent; the API carries the rest.

Grants made

The 10 largest by cash amount. The API serves every itemized grant.

Where these grants went next →

Grants received

The 10 largest by cash amount. The API serves every itemized grant.

Related organizations

From Schedule R Part II, where a filer lists the tax-exempt organizations it is related to by control. It does not record shared board members or money.

Declared on its 2024 return

Declared as related by

Taxable family

From Schedule R Parts I, III and IV: entities that legally are the filer, and taxable partnerships, corporations and trusts it is related to. These record ownership and control, not shared board members or money.

Disregarded entities on its 2024 return

  • CHILDREN'S GMP LLC

    BIOTHERAPEUTICS MANUFACTURING · TN · income $6,316 · assets $2,980,340

  • THANKS & GIVING LLC

    ROYALTY INCOME FROM RECORD SALES · TN · income $0 · assets $9,822

  • THE RIGHT WORDS LLC

    ROYALTY INCOME FROM BOOK SALES · NY · income $0 · assets $0

  • ST JUDE CHILDREN'S RESEARCH HOSPITAL GRADUATE SCHOOL OF BIOMEDICAL SCIENCES

    HIGHER EDUCATION · TN · income $337,819 · assets $4,698,039

  • ST JUDE CHILDREN'S RESEARCH HOSPITAL HOME CARE LLC

    HOME HEALTH SERVICES · TN · income $79,133 · assets $1,011,150

  • ST JUDE GLOBAL OPERATIONS PLATFORM LLC

    GLOBAL ACTIVITIES · DE · income -$2,929 · assets $3,792,186

Other IRS files

Auto-Revocation List

Not listed. The IRS publishes this list for organizations whose exemption was automatically revoked for failing to file for three consecutive years.

Publication 78

Listed as of 13 October 2026, under deductibility PC.

These are two separate IRS files on two separate schedules, shown as published and not reconciled with each other. Neither is a statement about whether a contribution is deductible today: 19,245 organizations appear in Publication 78 while the IRS's own revocation file lists them as currently revoked, more than half of those revoked before 2019. Absence from Publication 78 is evidence of nothing, and presence is not evidence either. Verify current status with the IRS before relying on it.

What this page reflects

The registration facts above come from the IRS Business Master File published 9 November 2026 and read 9 November 2026, for every organization at once. Returns through tax year 2024, the newest we have parsed for this organization.