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INSTITUTE FOR SYSTEMS BIOLOGY

EIN 91-2003593 SEATTLE, WA

Revenue 2024
$42,255,091
Expenses 2024
$47,550,054

Program services were 71.1% of total expenses calculated — Part IX's program-services column over total expenses, both as filed.

As filed

Subsection
03
NTEE code
U500
Classification
8000
Street
401 TERRY AVE N

These codes are the IRS's own and are shown exactly as filed. What each one means is in the Business Master File documentation (opens in a new tab).

Officers and directors · 2024

As listed in Part VII of the 2024 return, in the order the filer printed them. Each return names its own; this is not a roster the organization keeps with us.

  • WASIF RASHEED

    DIRECTOR - THRU 3/24

    Total calculated
    $3,178,068
    From this org
    $0
    From related orgs
    $3,164,494
    Other
    $13,574
    Hours/week
    0.5 + 64.5 related

    Schedule J breakdown matched by us

    Base
    $0 + $238,066 related
    Bonus
    $0 + $1,556,981 related
    Other
    $0 + $1,369,447 related
    Deferred
    $0 + $7,763 related
    Nontaxable benefits
    $0 + $5,811 related
    Filer's total
    $0 + $3,178,068 related

  • HODA ASMAR MD

    DIRECTOR (PART YEAR)

    Total calculated
    $2,697,869
    From this org
    $0
    From related orgs
    $2,675,264
    Other
    $22,605
    Hours/week
    0.5 + 64.5 related

    Schedule J breakdown matched by us

    Base
    $0 + $948,833 related
    Bonus
    $0 + $1,243,643 related
    Other
    $0 + $482,788 related
    Deferred
    $0 + $15,525 related
    Nontaxable benefits
    $0 + $7,080 related
    Filer's total
    $0 + $2,697,869 related

  • ARI ROBICSEK MD

    DIRECTOR

    Total calculated
    $2,234,491
    From this org
    $0
    From related orgs
    $2,018,676
    Other
    $215,815
    Hours/week
    0.5 + 64.5 related

    Schedule J breakdown matched by us

    Base
    $0 + $726,741 related
    Bonus
    $0 + $1,023,060 related
    Other
    $0 + $268,875 related
    Deferred
    $0 + $207,113 related
    Nontaxable benefits
    $0 + $8,702 related
    Filer's total
    $0 + $2,234,491 related

  • JIM MARTIN

    DIRECTOR - THRU 6/24

    Total calculated
    $917,253
    From this org
    $0
    From related orgs
    $820,365
    Other
    $96,888
    Hours/week
    0.5 + 54.5 related

    Schedule J breakdown matched by us

    Base
    $0 + $463,263 related
    Bonus
    $0 + $290,109 related
    Other
    $0 + $66,993 related
    Deferred
    $0 + $88,541 related
    Nontaxable benefits
    $0 + $8,347 related
    Filer's total
    $0 + $917,253 related

  • JAMES R HEATH PHD

    PRESIDENT/PROFESSOR

    Total calculated
    $565,815
    From this org
    $509,772
    From related orgs
    $0
    Other
    $56,043
    Hours/week
    55

    Schedule J breakdown matched by us

    Base
    $493,486
    Bonus
    $0
    Other
    $16,286
    Deferred
    $27,600
    Nontaxable benefits
    $28,443
    Filer's total
    $565,815

  • NITIN BALIGA PHD

    SVP DIR OF INTEGRATIVE SCIENCE/PROF

    Total calculated
    $407,040
    From this org
    $343,731
    From related orgs
    $0
    Other
    $63,309
    Hours/week
    55

    Schedule J breakdown matched by us

    Base
    $341,929
    Bonus
    $0
    Other
    $1,802
    Deferred
    $27,600
    Nontaxable benefits
    $35,709
    Filer's total
    $407,040

  • KATHY SCANLAN

    COO/TREASURER

    Total calculated
    $384,719
    From this org
    $323,595
    From related orgs
    $0
    Other
    $61,124
    Hours/week
    55

    Schedule J breakdown matched by us

    Base
    $319,778
    Bonus
    $0
    Other
    $3,817
    Deferred
    $26,250
    Nontaxable benefits
    $34,874
    Filer's total
    $384,719

  • ANDREW MAGIS

    DIRECTOR OF DATA SCIENCE

    Total calculated
    $326,585
    From this org
    $282,804
    From related orgs
    $0
    Other
    $43,781
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $281,530
    Bonus
    $0
    Other
    $1,274
    Deferred
    $23,200
    Nontaxable benefits
    $20,581
    Filer's total
    $326,585

  • ROBERT L MORTIZ PHD

    PROFESSOR

    Total calculated
    $312,980
    From this org
    $271,421
    From related orgs
    $0
    Other
    $41,559
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $269,286
    Bonus
    $0
    Other
    $2,135
    Deferred
    $22,000
    Nontaxable benefits
    $19,559
    Filer's total
    $312,980

  • SUI HUANG MD PHD

    PROFESSOR

    Total calculated
    $288,315
    From this org
    $237,123
    From related orgs
    $0
    Other
    $51,192
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $234,683
    Bonus
    $0
    Other
    $2,440
    Deferred
    $19,200
    Nontaxable benefits
    $31,992
    Filer's total
    $288,315

  • ERIKA KREGER

    DIRECTOR OF DEVELOPMENT

    Total calculated
    $248,911
    From this org
    $186,033
    From related orgs
    $0
    Other
    $62,878
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $182,401
    Bonus
    $2,500
    Other
    $1,132
    Deferred
    $15,444
    Nontaxable benefits
    $47,434
    Filer's total
    $248,911

  • AMY COMPTON-PHILLIPS MD

    DIRECTOR

    Total calculated
    $231,120
    From this org
    $0
    From related orgs
    $231,120
    Other
    $0
    Hours/week
    0.5

    Schedule J breakdown matched by us

    Base
    $0
    Bonus
    $0
    Other
    $0 + $231,120 related
    Deferred
    $0
    Nontaxable benefits
    $0
    Filer's total
    $0 + $231,120 related

  • LEROY HOOD MD PHD

    DIRECTOR

    Total calculated
    $193,125
    From this org
    $187,500
    From related orgs
    $0
    Other
    $5,625
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $187,500
    Bonus
    $0
    Other
    $0
    Deferred
    $5,625
    Nontaxable benefits
    $0
    Filer's total
    $193,125

  • NAEHA SUBRAMANIAN PHD

    ASSOCIATE PROFESSOR

    Total calculated
    $209,744
    From this org
    $181,654
    From related orgs
    $0
    Other
    $28,090
    Hours/week
    50

    Schedule J breakdown matched by us

    Base
    $180,711
    Bonus
    $0
    Other
    $943
    Deferred
    $14,480
    Nontaxable benefits
    $13,610
    Filer's total
    $209,744

  • CHARLES WATTS MD

    BOARD CHAIR

    Total calculated
    $0
    Hours/week
    1

  • BRIAN V TURNER

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • CRAIG MUNDIE

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • DANIEL T LING

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • DAVID SABEY

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • DOUGLAS HOWE

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • HEATHER REDMAN

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • JOHN SABEY

    DIRECTOR (PART YEAR)

    Total calculated
    $0
    Hours/week
    0.5

  • MELANIE L MAYER PHD

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • NANCY ALLBRITTON MD PHD

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

  • ROGER PERLMUTTER MD PHD

    DIRECTOR

    Total calculated
    $0
    Hours/week
    0.5

The first 25 listed. Compensation is as filed in Part VII: reportable pay from this organization and from related organizations, other compensation, and hours per week. The total, marked calculated, is our sum of the three dollar columns, with a blank column counted as $0; the form itself has no total. On a Form 990-EZ the columns are Part IV's instead — compensation, contributions to benefit plans, and expense account — and the total sums those. A Schedule J breakdown is as filed: base pay, bonus, other, deferred compensation and nontaxable benefits from this organization, with any from related organizations beside each, and the filer's own total. It is shown with the Part VII listing of the same name on the same return. The form gives no key between the two, so that pairing is ours, and is marked matched by us. Earlier years are each on their own filing page.

Filings

  • 2024
    Revenue
    $42,255,091
    Expenses
    $47,550,054
    Contributions
    $37,859,571
    Grants paid
    $0
  • 2023
    Revenue
    $43,611,326
    Expenses
    $46,752,331
    Contributions
    $40,929,618
    Grants paid
    $0
  • 2022
    Revenue
    $37,072,888
    Expenses
    $41,968,785
    Contributions
    $34,972,830
    Grants paid
    $0

The four totals the IRS asks for on Part I of the Form 990, as filed. A dash means the figure was not present on the return — not that it was zero.

Other returns filed

  • 2024 · 990-T

    Revenue
    not reported
    Expenses
    not reported
    Assets (EOY)
    not reported

  • 2023 · 990-T

    Revenue
    not reported
    Expenses
    not reported
    Assets (EOY)
    not reported

  • 2022 · 990-T

    Revenue
    not reported
    Expenses
    not reported
    Assets (EOY)
    not reported

Nonprofiteer parses the Form 990 only. These returns are recorded from the IRS e-file index, so their figures were extracted by that index rather than read from the return here — treat them as a different source from the filings above, not as more of the same record. A dash means the index carries no figure; Form 990-T listings carry none at all.

Grants made

No itemized grants to organizations. Schedule I is filed only by organizations that granted more than $5,000 to a recipient, so most filers have none.

Grants received

  • MAYO CLINIC GROUP RETURN

    $1,007,351

    2022 SUPPORT CHARITABLE PURPOSE

  • PROVIDENCE HEALTH & SERVICES WASHINGTON

    $741,940

    2022 OPERATIONAL SUPPORT

  • PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY

    $547,924

    2022 SUPPORT RESEARCH IN FIELD OF CANCER IMMUNOTHERAPY

  • MAYO CLINIC GROUP RETURN

    $445,307

    2023 SUPPORT RESEARCH PROGRAM

  • SAGE BIONETWORKS

    $379,595

    2023 CRI Immune Atlas4: Platform for immune-oncology research and data sharing. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them.

  • PRESIDENT AND FELLOWS OF HARVARD COLLEGE

    $361,086

    2022 SPONSORED RESEARCH SUB-AWARD

  • SEATTLE CHILDRENS HOSPITAL

    $349,566

    2022 PEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD

  • CORNELL UNIVERSITY

    $343,541

    2022 Research

  • EVERY CURE INC

    $309,022

    2024 ISB WILL CURATE, EVALUATE, AND INTEGRATE LARGE BIOMEDICAL DATASETS INTO EVERY CURE'S KNOWLEDGE GRAPH, FOCUSING ON DATA QUALITY AND ONTOLOGY HARMONIZATION. THEY WILL PERFORM MANUAL CURATION, CROSS-VALIDATION, AND DEVELOPMENT OF PROTOCOLS TO ENSURE RELIABLE DRUG, DISEASE, AND MOLECULAR ASSOCIATIONS. THEIR WORK ENSURES THE SPOKE DATABASE AND OTHER KEY SOURCES ARE INCORPORATED INTO A ROBUST COMPUTATIONAL FRAMEWORK FOR DRUG REPURPOSING.

  • SAGE BIONETWORKS

    $289,400

    2022 CRI Immune Atlas: Platform for immune-oncology research and data sharing phase 2 and 3. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them.

The 10 largest by cash amount. The API serves every itemized grant.

Related organizations

From Schedule R Part II, where a filer lists the tax-exempt organizations it is related to by control. It does not record shared board members or money.

Declared on its 2024 return

The first 25 as filed. The return lists every one.

Declared as related by

The most recent declarers. The API serves every row.

Other IRS files

Auto-Revocation List

Not listed. The IRS publishes this list for organizations whose exemption was automatically revoked for failing to file for three consecutive years.

Publication 78

Listed as of 10 September 2026, under deductibility PC.

These are two separate IRS files on two separate schedules, shown as published and not reconciled with each other. Neither is a statement about whether a contribution is deductible today: 19,245 organizations appear in Publication 78 while the IRS's own revocation file lists them as currently revoked, more than half of those revoked before 2019. Absence from Publication 78 is evidence of nothing, and presence is not evidence either. Verify current status with the IRS before relying on it.