Lists Largest by total revenue
Largest nonprofits in Missouri by total revenue
Organizations whose address on record is in Missouri, ranked by the total revenue on each one's most recent Form 990, 990-EZ or 990-PF that reports it, as filed. Tax years differ from row to row: each is that organization's latest such return. An amended return is counted once, replaced by its amendment.
Not every nonprofit can appear. Churches and most religious congregations are not required to file a 990, and organizations with gross receipts normally under $50,000 file the 990-N postcard, which reports no revenue.
Computed 2 November 2026.
Ranking
| Rank | Organization | Tax year | Total revenue |
|---|---|---|---|
| 1 | BJC HEALTH SYSTEM SAINT LOUIS, MO | 2024 | $11,251,316,536 |
| 2 | GOVERNMENT EMPLOYEES HEALTH ASSOCIATION INC LEES SUMMIT, MO | 2024 | $6,100,727,459 |
| 3 | WASHINGTON UNIVERSITY ST LOUIS, MO | 2023 | $5,204,380,540 |
| 4 | ASCENSION SETON SAINT LOUIS, MO | 2023 | $3,309,540,569 |
| 5 | ASCENSION HEALTH ALLIANCE SAINT LOUIS, MO | 2023 | $2,404,854,217 |
| 6 | CHILDRENS MERCY HOSPITAL KANSAS CITY, MO | 2024 | $2,340,991,656 |
| 7 | SSM HEALTH CARE ST LOUIS SAINT LOUIS, MO | 2024 | $2,192,307,272 |
| 8 | BJC HEALTH SYSTEM SAINT LOUIS, MO | 2024 | $2,042,365,571 |
| 9 | MERCY HOSPITALS EAST COMMUNITIES CHESTERFIELD, MO | 2024 | $1,974,869,337 |
| 10 | LESTER E COX MEDICAL CENTER SPRINGFIELD, MO | 2024 | $1,960,936,555 |
| 11 | SACRED HEART HEALTH SYSTEM INC SAINT LOUIS, MO | 2023 | $1,658,437,784 |
| 12 | ST VINCENT HOSPITAL & HEALTH CARE SAINT LOUIS, MO | 2024 | $1,655,182,680 |
| 13 | MHM SUPPORT SERVICES CHESTERFIELD, MO | 2023 | $1,540,453,031 |
| 14 | MERCY HOSPITAL SPRINGFIELD SPRINGFIELD, MO | 2024 | $1,453,548,711 |
| 15 | SSM HEALTH CARE CORPORATION SAINT LOUIS, MO | 2024 | $1,391,036,296 |
| 16 | ASCENSION HEALTH-IS INC SAINT LOUIS, MO | 2023 | $1,274,740,314 |
| 17 | SAINT THOMAS WEST HOSPITAL SAINT LOUIS, MO | 2023 | $1,250,375,354 |
| 18 | PRESENCE CHICAGO HOSPITALS NETWORK SAINT LOUIS, MO | 2023 | $1,225,026,280 |
| 19 | ST LOUIS UNIVERSITY SAINT LOUIS, MO | 2024 | $1,195,599,660 |
| 20 | ST LUKES HOSPITAL OF KANSAS CITY KANSAS CITY, MO | 2023 | $1,157,790,152 |
| 21 | SSM HEALTH CARE OF OKLAHOMA INC SAINT LOUIS, MO | 2024 | $1,121,270,362 |
| 22 | SSM-SLUH INC SAINT LOUIS, MO | 2024 | $947,923,142 |
| 23 | TRUMAN MEDICAL CENTER INCORPORATED KANSAS CITY, MO | 2024 | $892,047,111 |
| 24 | HEARTLAND REGIONAL MEDICAL CENTER SAINT JOSEPH, MO | 2024 | $883,407,770 |
| 25 | DELTA DENTAL OF MISSOURI ST LOUIS, MO | 2024 | $805,510,567 |
| 26 | MERCY CLINIC EAST COMMUNITIES CHESTERFIELD, MO | 2024 | $804,629,365 |
| 27 | GREATER KANSAS CITY COMMUNITY FOUNDATION KANSAS CITY, MO | 2024 | $781,787,887 |
| 28 | SSM HEALTH CARE OF WISCONSIN INC SAINT LOUIS, MO | 2024 | $770,222,978 |
| 29 | ASCENSION VIA CHRISTI HOSPITALS WICHITA INC SAINT LOUIS, MO | 2023 | $759,068,346 |
| 30 | GREATER HORIZONS KANSAS CITY, MO | 2024 | $754,144,636 |
| 31 | COLUMBIA ST MARYS HOSPITAL MILWAUKEE INC SAINT LOUIS, MO | 2024 | $724,039,616 |
| 32 | FREEMAN HEALTH SYSTEM JOPLIN, MO | 2024 | $709,601,151 |
| 33 | MERCY HOSPITAL SOUTH SAINT LOUIS, MO | 2024 | $709,067,431 |
| 34 | SAINT FRANCIS MEDICAL CENTER CPE GIRARDEAU, MO | 2023 | $695,085,743 |
| 35 | ST LUKES EPISCOPAL-PRESBYTERIAN HOSPITAL CHESTERFIELD, MO | 2024 | $685,484,744 |
| 36 | ST MARYS HEALTH INC DBA ASCENSION SAINT LOUIS, MO | 2024 | $669,333,941 |
| 37 | COMPASS HEALTH INC CLINTON, MO | 2024 | $663,472,344 |
| 38 | AGNESIAN HEALTHCARE INC SAINT LOUIS, MO | 2024 | $584,413,789 |
| 39 | MERCY CLINIC SPRINGFIELD COMMUNITIES CHESTERFIELD, MO | 2024 | $570,849,481 |
| 40 | SAINT LUKES PHYSICIAN GROUP INC KANSAS CITY, MO | 2023 | $562,469,307 |
| 41 | ST AGNES HEALTHCARE INC SAINT LOUIS, MO | 2024 | $536,687,047 |
| 42 | SAINT THOMAS RUTHERFORD HOSPITAL SAINT LOUIS, MO | 2023 | $512,857,503 |
| 43 | ALEXIAN BROTHERS MEDICAL CENTER SAINT LOUIS, MO | 2023 | $482,008,501 |
| 44 | ST VINCENTS MEDICAL CENTER INC SAINT LOUIS, MO | 2023 | $453,752,796 |
| 45 | SSM CARDINAL GLENNON CHILDRENS HOSPITAL SAINT LOUIS, MO | 2024 | $441,283,899 |
| 46 | CH ALLIED SERVICES INC COLUMBIA, MO | 2024 | $438,261,156 |
| 47 | SOUTHEAST HOSPITAL CPE GIRARDEAU, MO | 2024 | $404,529,005 |
| 48 | BEACON KALAMAZOO INC SAINT LOUIS, MO | 2023 | $402,319,537 |
| 49 | COXHEALTH SPRINGFIELD, MO | 2024 | $394,598,058 |
| 50 | ST ALEXIUS MEDICAL CENTER SAINT LOUIS, MO | 2024 | $389,316,421 |
| 51 | ASCENSION SE WISCONSIN HOSPITAL INC SAINT LOUIS, MO | 2023 | $388,395,661 |
| 52 | SAINT LUKES EAST HOSPITAL LEES SUMMIT, MO | 2023 | $376,201,191 |
| 53 | SAINT THOMAS MEDICAL PARTNERS SAINT LOUIS, MO | 2024 | $366,184,545 |
| 54 | SSM HEALTH CARE GROUP SAINT LOUIS, MO | 2024 | $351,909,349 |
| 55 | MISSOURI VALLEY LINE CONSTRUCTORS KANSAS CITY, MO | 2024 | $350,746,966 |
| 56 | ST VINCENT MEDICAL GROUP INC SAINT LOUIS, MO | 2024 | $338,620,643 |
| 57 | ASCENSION HEALTH PROFESSIONAL AND GENERAL LIABILITY SELF-INSURANCE SAINT LOUIS, MO | 2023 | $335,867,103 |
| 58 | HANNIBAL REGIONAL HEALTHCARE SYSTEM INC HANNIBAL, MO | 2024 | $325,399,388 |
| 59 | SKAGGS COMMUNITY HOSPITAL ASSOCIATION BRANSON, MO | 2024 | $314,979,655 |
| 60 | MERCY HOSPITAL JOPLIN JOPLIN, MO | 2023 | $308,748,135 |
| 61 | ASCENSION ALL SAINTS HOSPITAL INC SAINT LOUIS, MO | 2023 | $308,158,113 |
| 62 | NATIONAL ELECTRICAL CONTRACTORS ASSOCIATION INC KANSAS CITY, MO | 2024 | $306,712,395 |
| 63 | CARPENTERS HEALTH & WELFARE TRUST FUND OF ST LOUIS ST LOUIS, MO | 2024 | $302,848,410 |
| 64 | ASCENSION PROVIDENCE SAINT LOUIS, MO | 2023 | $301,726,602 |
| 65 | MERCY HOSPITAL JEFFERSON CRYSTAL CITY, MO | 2024 | $300,175,557 |
| 66 | SETON FAMILY OF DOCTORS SAINT LOUIS, MO | 2024 | $284,323,550 |
| 67 | SAINT LUKES HEALTH SYSTEM INC KANSAS CITY, MO | 2023 | $283,168,180 |
| 68 | CONCORDIA HEALTH PLAN SAINT LOUIS, MO | 2025 | $278,771,265 |
| 69 | ST VINCENT CARMEL HOSPITAL INC SAINT LOUIS, MO | 2023 | $277,310,405 |
| 70 | SSM HEALTH BUSINESSES SAINT LOUIS, MO | 2024 | $273,933,110 |
| 71 | LAKE REGIONAL HEALTH SYSTEM OSAGE BEACH, MO | 2024 | $273,472,502 |
| 72 | GOOD SAMARITAN REGIONAL HEALTH CENTER SAINT LOUIS, MO | 2024 | $264,543,787 |
| 73 | FELLOWSHIP OF CHRISTIAN ATHLETES KANSAS CITY, MO | 2024 | $262,386,103 |
| 74 | ST LUKES - ST VINCENTS HEALTHCAREINC SAINT LOUIS, MO | 2023 | $262,136,482 |
| 75 | STIFEL CHARITABLE INC SAINT LOUIS, MO | 2025 | $261,457,767 |
| 76 | OZARKS MEDICAL CENTER WEST PLAINS, MO | 2024 | $261,442,966 |
| 77 | First Community Credit Union Chesterfield, MO | 2024 | $256,311,892 |
| 78 | PRESENCE ST MARYS HOSPITAL PRESENCE CENTRAL AND SUBURBAN HOSPITALS NET SAINT LOUIS, MO | 2024 | $255,990,346 |
| 79 | ASCENSION MEDICAL GROUP-SOUTHEAST WISCONSIN INC SAINT LOUIS, MO | 2023 | $254,694,727 |
| 80 | LUTHERAN SENIOR SERVICES SAINT LOUIS, MO | 2024 | $254,513,817 |
| 81 | CENTRAL ELECTRIC POWER COOPERATIVE JEFFERSON CTY, MO | 2023 | $253,080,355 |
| 82 | MERS MISSOURI GOODWILL INDUSTRIES SAINT LOUIS, MO | 2023 | $247,495,406 |
| 83 | BURRELL INC SPRINGFIELD, MO | 2023 | $242,630,658 |
| 84 | A T STILL UNIVERSITY OF HEALTH SCIENCES KIRKSVILLE, MO | 2024 | $238,524,037 |
| 85 | THE MONROE CLINIC INC SAINT LOUIS, MO | 2024 | $237,133,051 |
| 86 | SAINT LUKES NORTH HOSPITAL KANSAS CITY, MO | 2023 | $233,411,515 |
| 87 | ASCENSION HEALTH SAINT LOUIS, MO | 2023 | $233,008,223 |
| 88 | HORIZON HOUSING FOUNDATION SAINT LOUIS, MO | 2024 | $230,593,544 |
| 89 | MISSOURI CHAMBER FEDERATION BENEFIT PLAN TRUST JEFFERSON CTY, MO | 2024 | $228,531,344 |
| 90 | MERCY CLINIC OKLAHOMA COMMUNITIES CHESTERFIELD, MO | 2024 | $225,717,190 |
| 91 | COX HEALTH SYSTEMS INSURANCE COMPANY SPRINGFIELD, MO | 2024 | $211,831,984 |
| 92 | DELL CHILDRENS MEDICAL GROUP SAINT LOUIS, MO | 2024 | $208,342,878 |
| 93 | PATTERSON FAMILY FOUNDATION KANSAS CITY, MO | 2024 | $206,307,740 |
| 94 | ST ANTHONY SHAWNEE HOSPITAL INC SAINT LOUIS, MO | 2024 | $205,517,992 |
| 95 | ASCENSION HEALTH TEXAS SAINT LOUIS, MO | 2024 | $202,761,921 |
| 96 | UNIVERSITY HEALTH PHYSICIANS KANSAS CITY, MO | 2023 | $202,283,957 |
| 97 | SAINT FRANCIS HEALTHCARE SYSTEM CPE GIRARDEAU, MO | 2023 | $200,845,859 |
| 98 | EWING MARION KAUFFMAN FOUNDATION KANSAS CITY, MO | 2024 | $196,860,585 |
| 99 | ST VINCENT ANDERSON REGIONAL HOSPITAL INC SAINT LOUIS, MO | 2024 | $192,591,418 |
| 100 | ASCENSION WELFARE BENEFITS TRUST SAINT LOUIS, MO | 2024 | $191,430,760 |